Jumbo bacteriophages: an overview

Y Yuan, M Gao - Frontiers in microbiology, 2017 - frontiersin.org
Tailed bacteriophages with genomes larger than 200 kbp are classified as Jumbo phages,
and are rarely isolated by conventional methods. These phages are designated “jumbo” …

Bacteriophages and phage-derived proteins–application approaches

Z Drulis-Kawa, G Majkowska-Skrobek… - Current medicinal …, 2015 - ingentaconnect.com
Currently, the bacterial resistance, especially to most commonly used antibiotics has proved
to be a severe therapeutic problem. Nosocomial and community-acquired infections are …

Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas aeruginosa by direct lytic replication

E Maffei, AK Woischnig, MR Burkolter, Y Heyer… - Nature …, 2024 - nature.com
Bacteriophages are ubiquitous viral predators that have primarily been studied using fast-
growing laboratory cultures of their bacterial hosts. However, microbial life in nature is …

Emerging aspects of jumbo bacteriophages

A Nazir, A Ali, H Qing, Y Tong - Infection and drug resistance, 2021 - Taylor & Francis
The bacteriophages have been explored at a huge scale as a model system for their
applications in many biological-related fields. Jumbo phages with a large genome size from …

vB_PaeM_MIJ3, a Novel Jumbo Phage Infecting Pseudomonas aeruginosa, Possesses Unusual Genomic Features

M Imam, B Alrashid, F Patel, ASA Dowah… - Frontiers in …, 2019 - frontiersin.org
Phages are the most abundant biological entity on Earth. There are many variants in phage
virion sizes, morphology, and genome sizes. Large virion sized phages, with genome sizes …

A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections

K Danis-Wlodarczyk, D Vandenheuvel, HB Jang… - Scientific reports, 2016 - nature.com
Bacteriophage therapy is currently resurging as a potential complement/alternative to
antibiotic treatment. However, preclinical evaluation lacks streamlined approaches. We here …

Investigation of a Large Collection of Pseudomonas aeruginosa Bacteriophages Collected from a Single Environmental Source in Abidjan, Côte d'Ivoire

C Essoh, L Latino, C Midoux, Y Blouin, G Loukou… - PloS one, 2015 - journals.plos.org
Twenty two distinct bacteriophages were isolated from sewage water from five locations in
the city of Abidjan, Côte d'Ivoire over a two-year period, using a collection of Pseudomonas …

Phage phiKZ—the first of giants

V Krylov, M Bourkaltseva, E Pleteneva, O Shaburova… - Viruses, 2021 - mdpi.com
The paper covers the history of the discovery and description of phiKZ, the first known giant
bacteriophage active on Pseudomonas aeruginosa. It also describes its unique features …

Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages

C Lood, K Danis‐Wlodarczyk… - Environmental …, 2020 - Wiley Online Library
Summary Pseudomonas virus vB_PaeM_PA5oct is proposed as a model jumbo
bacteriophage to investigate phage‐bacteria interactions and is a candidate for phage …

In vitro and in vivo antibacterial activity of environmental bacteriophages against Pseudomonas aeruginosa strains from cystic fibrosis patients

T Olszak, P Zarnowiec, W Kaca… - Applied microbiology …, 2015 - Springer
The goal of the study was to determine the relationship between in vitro/in vivo efficacy of
environmental Pseudomonas phages and certain phenotypical properties of Pseudomonas …