Background and study aims Antireflux mucosectomy (ARMS) and antireflux mucosal
ablation (ARMA) are new endoscopic procedures for patients with gastroesophageal reflux …

Treatable traits is a personalised medicine approach to the management of airway disease.
Assessing traits within the three domains of pulmonary, extra pulmonary and …

Background Digestive diseases are very common worldwide and account for considerable
health care use and expenditures. However, there are no global population-based estimates …

Background Gastro-oesophageal reflux disease (GORD) is associated with idiopathic
pulmonary fibrosis (IPF) in observational studies. It is not known if this association arises …

BACKGROUND Fexuprazan, a novel potassium-competitive acid blocker, reversibly
suppresses the K+/H+-ATPase enzyme in proton pumps within gastric parietal cells …

Background Gastroesophageal reflux disease (GERD) and reflux esophagitis remain
problems after peroral endoscopic myotomy (POEM). This study aimed to elucidate the risk …

Background No detailed quantitative global, regional, or national estimates of the disability‐
adjusted life years (DALYs) of type 2 diabetes mellitus (T2DM) are available. Methods We …

Background Tegoprazan is a novel, fast‐and long‐acting potassium‐competitive acid
blocker that suppresses gastric acid secretion, which could benefit patients with non‐erosive …

Herein, we report a food‐effect study of vonoprazan, an oral potassium‐competitive acid
blocker. In a phase 1, randomized, open‐label, crossover study, healthy subjects received a …

Objectives To quantify the burden and variation trends of cancers in children under 5 years
at the global, regional, and national levels from 1990 to 2019. Methods Epidemiological data …