Nanomaterials for wound healing and infection control

MM Mihai, MB Dima, B Dima, AM Holban - Materials, 2019 - mdpi.com
Wound healing has been intensely studied in order to develop an “ideal” technique that
achieves expeditious recovery and reduces scarring to the minimum, thus ensuring function …

Antifouling and antimicrobial biomaterials: an overview

I Francolini, C Vuotto, A Piozzi, G Donelli - Apmis, 2017 - Wiley Online Library
The use of implantable medical devices is a common and indispensable part of medical
care for both diagnostic and therapeutic purposes. However, as side effect, the implant of …

Options and limitations in clinical investigation of bacterial biofilms

M Magana, C Sereti, A Ioannidis… - Clinical Microbiology …, 2018 - Am Soc Microbiol
Bacteria can form single-and multispecies biofilms exhibiting diverse features based upon
the microbial composition of their community and microenvironment. The study of bacterial …

Glycoside hydrolases degrade polymicrobial bacterial biofilms in wounds

D Fleming, L Chahin, K Rumbaugh - Antimicrobial agents and …, 2017 - Am Soc Microbiol
The persistent nature of chronic wounds leaves them highly susceptible to invasion by a
variety of pathogens that have the ability to construct an extracellular polymeric substance …

Antimicrobial susceptibility testing of antimicrobial peptides to better predict efficacy

DK Mercer, MDT Torres, SS Duay, E Lovie… - Frontiers in cellular …, 2020 - frontiersin.org
During the development of antimicrobial peptides (AMP) as potential therapeutics,
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …

The prospects of antimicrobial coated medical implants

A Shahid, B Aslam, S Muzammil… - Journal of applied …, 2021 - journals.sagepub.com
The implants are increasingly being a part of modern medicine in various surgical
procedures for functional or cosmetic purposes. The progressive use of implants is …

Challenges and innovations in treating chronic and acute wound infections: from basic science to clinical practice

X Ding, Q Tang, Z Xu, Y Xu, H Zhang, D Zheng… - Burns & …, 2022 - academic.oup.com
Acute and chronic wound infection has become a major worldwide healthcare burden
leading to significantly high morbidity and mortality. The underlying mechanism of infections …

[HTML][HTML] Nanobiotechnology: applications in chronic wound healing

T Jiang, Q Li, J Qiu, J Chen, S Du, X Xu… - International journal …, 2022 - ncbi.nlm.nih.gov
Wounds occur when skin integrity is broken and the skin is damaged. With progressive
changes in the disease spectrum, the acute wounds caused by mechanical trauma have …

Novel approaches to the treatment of bacterial biofilm infections

G Hughes, MA Webber - British journal of pharmacology, 2017 - Wiley Online Library
Bacterial infection remains a major challenge to healthcare and is responsible for significant
morbidity and mortality. This situation is becoming complicated by an increasingly ageing …

Considerations and caveats in anti-virulence drug development

D Maura, AE Ballok, LG Rahme - Current opinion in microbiology, 2016 - Elsevier
Highlights•ESKAPE bacteria are ideal candidates for anti-virulence drugs due to their multi-
drug resistance.•Careful target selection to avoid resistance and maximize anti-virulence …