Fluorine and fluorinated motifs in the design and application of bioisosteres for drug design

NA Meanwell - Journal of medicinal chemistry, 2018 - ACS Publications
The electronic properties and relatively small size of fluorine endow it with considerable
versatility as a bioisostere and it has found application as a substitute for lone pairs of …

Chemical nematicides: Recent research progress and outlook

J Chen, QX Li, B Song - Journal of Agricultural and Food …, 2020 - ACS Publications
Plant-parasitic nematodes have caused huge economic losses to agriculture worldwide and
seriously threaten the sustainable development of modern agriculture. Chemical …

Weed management in 2050: Perspectives on the future of weed science

JH Westwood, R Charudattan, SO Duke… - Weed …, 2018 - cambridge.org
The discipline of weed science is at a critical juncture. Decades of efficient chemical weed
control have led to a rise in the number of herbicide-resistant weed populations, with few …

New reduced-risk agricultural nematicides-rationale and review

J Desaeger, C Wram, I Zasada - Journal of Nematology, 2020 - sciendo.com
The last decade has seen a sharp increase in nematicide research in the agricultural
industry. As a result, several new synthetic nematicides have become available to growers …

Effects of Fungicide and Herbicide Chemical Exposure on Apis and Non-Apis Bees in Agricultural Landscape

J Belsky, NK Joshi - Frontiers in Environmental Science, 2020 - frontiersin.org
Fungicide and herbicide chemistries are commonly applied in agricultural production
systems and other agricultural landscapes during flowering periods, which are concurrent …

Novel pyrazole-4-acetohydrazide derivatives potentially targeting fungal succinate dehydrogenase: design, synthesis, three-dimensional quantitative structure–activity …

X Wang, M Wang, L Han, F Jin, J Jiao… - Journal of Agricultural …, 2021 - ACS Publications
Succinate dehydrogenase inhibitors (SDHIs) have emerged in fungicide markets as one of
the fastest-growing categories that are widely applied in agricultural production for crop …

Review on the discovery of novel natural herbicide safeners

XY Leng, LX Zhao, S Gao, F Ye… - Journal of Agricultural and …, 2023 - ACS Publications
The phytotoxicity of herbicides on crops is a major dilemma in agricultural production.
Fortunately, the emergence of herbicide safeners is an excellent solution to this challenge …

High frequency monitoring of pesticides in runoff water to improve understanding of their transport and environmental impacts

M Lefrancq, A Jadas-Hécart, I La Jeunesse… - Science of the Total …, 2017 - Elsevier
Rainfall-induced peaks in pesticide concentrations can occur rapidly. Low frequency
sampling may therefore largely underestimate maximum pesticide concentrations and …

Expedient discovery for novel antifungal leads targeting succinate dehydrogenase: pyrazole-4-formylhydrazide derivatives bearing a diphenyl ether fragment

X Wang, A Wang, L Qiu, M Chen, A Lu… - Journal of Agricultural …, 2020 - ACS Publications
The pyrazole-4-carboxamide scaffold containing a flexible amide chain has emerged as the
molecular skeleton of highly efficient agricultural fungicides targeting succinate …

Fragmenlt recombination design, synthesis, and safener activity of novel ester-substituted pyrazole derivatives

L Jia, S Gao, YY Zhang, LX Zhao, Y Fu… - Journal of Agricultural …, 2021 - ACS Publications
Fenoxaprop-p-ethyl (FE), a type of acetyl-CoA carboxylase (ACCase) inhibitor, has been
extensively applied to a variety of crop plants. It can cause damage to wheat (Triticum …