[HTML][HTML] Gut microbiota imbalance and colorectal cancer

J Gagnière, J Raisch, J Veziant, N Barnich… - World journal of …, 2016 - ncbi.nlm.nih.gov
The gut microbiota acts as a real organ. The symbiotic interactions between resident micro-
organisms and the digestive tract highly contribute to maintain the gut homeostasis …

Escherichia coli ST131, an intriguing clonal group

MH Nicolas-Chanoine, X Bertrand… - Clinical microbiology …, 2014 - Am Soc Microbiol
In 2008, a previously unknown Escherichia coli clonal group, sequence type 131 (ST131),
was identified on three continents. Today, ST131 is the predominant E. coli lineage among …

Microbiota, inflammation and colorectal cancer

C Lucas, N Barnich, HTT Nguyen - International journal of molecular …, 2017 - mdpi.com
Colorectal cancer, the fourth leading cause of cancer-related death worldwide, is a
multifactorial disease involving genetic, environmental and lifestyle risk factors. In addition …

Phylogenetic background and habitat drive the genetic diversification of Escherichia coli

M Touchon, A Perrin, JAM De Sousa, B Vangchhia… - PLoS …, 2020 - journals.plos.org
Escherichia coli is mostly a commensal of birds and mammals, including humans, where it
can act as an opportunistic pathogen. It is also found in water and sediments. We …

Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli

M Desvaux, G Dalmasso, R Beyrouthy… - Frontiers in …, 2020 - frontiersin.org
Escherichia coli is a versatile bacterial species that includes both harmless commensal
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …

The population genetics of commensal Escherichia coli

O Tenaillon, D Skurnik, B Picard… - Nature reviews …, 2010 - nature.com
The primary habitat of Escherichia coli is the vertebrate gut, where it is the predominant
aerobic organism, living in symbiosis with its host. Despite the occurrence of recombination …

Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells

G Cuevas-Ramos, CR Petit, I Marcq… - Proceedings of the …, 2010 - National Acad Sciences
Escherichia coli is a normal inhabitant of the human gut. However, E. coli strains of
phylogenetic group B2 harbor a genomic island called “pks” that codes for the production of …

Gut microbiota in colorectal cancer: biological role and therapeutic opportunities

H Pandey, DWT Tang, SH Wong, D Lal - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the second-leading cause of cancer-related
deaths worldwide. In this review article, we examine the role of gut microbiota in the …

Sex and virulence in Escherichia coli: an evolutionary perspective

T Wirth, D Falush, R Lan, F Colles… - Molecular …, 2006 - Wiley Online Library
Pathogenic Escherichia coli cause over 160 million cases of dysentery and one million
deaths per year, whereas non‐pathogenic E. coli constitute part of the normal intestinal flora …

E. coli as an All-Rounder: The Thin Line Between Commensalism and Pathogenicity

A Leimbach, J Hacker, U Dobrindt - Between pathogenicity and …, 2013 - Springer
Escherichia coli is a paradigm for a versatile bacterial species which comprises harmless
commensal as well as different pathogenic variants with the ability to either cause intestinal …