The ultimate goal of radiation oncology is to eradicate tumours without toxicity to non-
malignant tissues. FLASH radiotherapy, or the delivery of ultra-high dose rates of radiation …

Ultrahigh–dose rate FLASH radiotherapy (FLASH-RT) is a potentially paradigm-shifting
treatment modality that holds the promise of expanding the therapeutic index for nearly any …

Cancer therapy with accelerated charged particles is one of the most valuable biomedical
applications of nuclear physics. The technology has vastly evolved in the past 50 years, the …

Purpose FLASH radiation therapy (FLASH-RT) is a promising radiation technique that uses
ultrahigh doses of radiation to increase the therapeutic window of the treatment. FLASH-RT …

Definition Flash radiotherapy (Flash-RT) is an innovative technique used in radiotherapy for
cancer treatment because it delivers an extremely high dose of radiation (> 40 Gy/s) to the …

FLASH radiotherapy, or the delivery of a dose at an ultra-high dose rate (> 40 Gy/s), has
recently emerged as a promising tool to enhance the therapeutic index in cancer treatment …

Particle therapies are becoming increasingly available clinically due to their beneficial
energy deposition profile, sparing healthy tissues. This may be further promoted with ultra …

The last several years have revealed increasing evidence of the immunomodulatory role of
radiation therapy. Radiotherapy reshapes the tumoral microenvironment can shift the …

Radiotherapy plays a pivotal role in the control and eradication of tumors, but it can also
induce radiation injury to surrounding normal tissues while targeting tumor cells. In recent …

Purpose FLASH proton pencil beam scanning (p-PBS) showed a reduction in mouse skin
toxicity and fibrosis when delivered as a single, uninterrupted, high-dose fraction. Clinical p …