Shared genetic risk factors for depression and stroke

F Zhao, Y Yue, H Jiang, Y Yuan - Progress in Neuro-Psychopharmacology …, 2019 - Elsevier
Background The comorbidity of major depressive disorder (MDD) and stroke are common in
clinic. There is a growing body of evidence suggesting a bi-directional relationship between …

Influences of genetic variants on stroke recovery: a meta-analysis of the 31,895 cases

N Math, TS Han, I Lubomirova, R Hill, P Bentley… - Neurological …, 2019 - Springer
Background The influences of genetic variants on functional clinical outcomes following
stroke are unclear. In order to reliably quantify these influences, we undertook a …

Angiotensin-converting enzyme gene insertion/deletion polymorphism and risk of ischemic stroke complication among patients with hypertension in the Ethiopian …

A Melake, N Berhane - Frontiers in Neurology, 2023 - frontiersin.org
Background Ischemic stroke is a complicated, multifaceted condition brought on by a
confluence of vascular, environmental, and genetic variables. The burden of ischemic stroke …

ACE inhibitors and their interaction with systems and molecules involved in metabolism

DL Silva-Velasco, LG Cervantes-Pérez… - Heliyon, 2024 - cell.com
The main function of the renin-angiotensin-aldosterone system (RAAS) is the regulation of
blood pressure; therefore, researchers have focused on its study to treat cardiovascular and …

ACE-triggered hypertension incites stroke: genetic, molecular, and therapeutic aspects

K Vasudeva, R Balyan, A Munshi - Neuromolecular medicine, 2020 - Springer
Stroke is the second largest cause of death worldwide. Angiotensin converting enzyme
(ACE) gene has emerged as an important player in the pathogenesis of hypertension and …

MiR-10a, 27a, 34b/c, and 300 Polymorphisms are Associated with Ischemic Stroke Susceptibility and Post-Stroke Mortality

CS Ryu, SH Oh, KO Lee, HS Park, HJ An, JY Lee… - Life, 2020 - mdpi.com
A recent study of the ischemic stroke described the roles played by miRNAs in the
downregulation of specific cell-cycle gene expression and it is thought to require the …

Genetics of ischemic stroke functional outcome

TP Carnwath, SL Demel, CJ Prestigiacomo - Journal of Neurology, 2024 - Springer
Ischemic stroke, which accounts for 87% of cerebrovascular accidents, is responsible for
massive global burden both in terms of economic cost and personal hardship. Many stroke …

Analysis of the association between polymorphisms within PAI-1 and ACE genes and ischemic stroke outcome after rt-PA therapy

MD Pjević, LB Bumbaširevic… - … of Pharmacy & …, 2019 - journals.library.ualberta.ca
Purpose: Treatment of Ischemic stroke (IS) in acute phase is based on the use of
thrombolytic rt-PA therapy. We aimed to determine whether different alleles and genotypes …

Genetic and lifestyle predictors of ischemic stroke severity and outcome

I Celap, N Nikolac Gabaj, V Demarin, V Basic Kes… - Neurological …, 2019 - Springer
Background Different models that include clinical variables and blood markers have been
investigated to predict acute ischemic stroke treatment course and recovery. Aim The aim of …

Genetic polymorphisms in a familial hypercholesterolemia population from North-Eastern Europe

A Maștaleru, SA Cojocariu, A Oancea… - Journal of Personalized …, 2022 - mdpi.com
(1) Background: Familial hypercholesterolemia (FH) is one of the most prevalent inherited
metabolic disorders. The purpose of the study was to investigate the role in cardiovascular …