Deregulation of autophagy is proposed to play a key pathogenic role in hepatocellular
carcinoma (HCC), the most common primary malignancy of the liver and the third leading …

Autophagy is considered a cytoprotective function in cancer therapy under certain conditions
and is a drug resistance mechanism that represents a clinical obstacle to successful cancer …

Abstract Purpose of Review Non-alcoholic fatty liver disease (NAFLD) is one of the most
common causes of chronic liver disease with rising prevalence worldwide. Herein, we …

Autophagy is an evolutionarily conserved process that plays a role in regulating
homeostasis under physiological conditions. However, dysregulation of autophagy is …

Autophagy is a catabolic process by which eukaryotic cells eliminate cytosolic materials
through vacuole-mediated sequestration and subsequent delivery to lysosomes for …

Despite advances in diagnostic tools and therapeutic options, treatment resistance remains
a challenge for many cancer patients. Recent studies have found evidence that autophagy …

The incidence and mortality of cancer are increasing, making it a leading cause of death
worldwide. Conventional treatments such as surgery, radiotherapy, and chemotherapy face …

Non-alcoholic fatty liver disease (NAFLD) will become a dominant cause of hepatocellular
carcinoma (HCC) in the coming decade. Whereas the exact molecular mechanisms …

The complicated stepwise lysosomal degradation process known as autophagy is in charge
of destroying and eliminating damaged organelles and defective cytoplasmic components …

Autophagy is an evolutionarily conserved cellular degradative process in which intracellular
components (cellular proteins and organelles) are engulfed in autophagosomes which then …