Hallmarks of pluripotency
Stem cells self-renew and generate specialized progeny through differentiation, but vary in
the range of cells and tissues they generate, a property called developmental potency …
the range of cells and tissues they generate, a property called developmental potency …
Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy
D Baksh, L Song, RS Tuan - Journal of cellular and molecular …, 2004 - Wiley Online Library
A considerable amount of retrospective data is available that describes putative
mesenchymal stem cells (MSCs). However, there is still very little knowledge available that …
mesenchymal stem cells (MSCs). However, there is still very little knowledge available that …
Mesenchymal stem cells avoid allogeneic rejection
Adult bone marrow derived mesenchymal stem cells offer the potential to open a new
frontier in medicine. Regenerative medicine aims to replace effete cells in a broad range of …
frontier in medicine. Regenerative medicine aims to replace effete cells in a broad range of …
Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells
RE Schwartz, M Reyes, L Koodie… - The Journal of …, 2002 - Am Soc Clin Investig
We have derived from normal human, mouse, and rat postnatal bone marrow primitive,
multipotent adult progenitor cells (MAPCs) that can differentiate into most mesodermal cells …
multipotent adult progenitor cells (MAPCs) that can differentiate into most mesodermal cells …
[PDF][PDF] In vitro hepatic differentiation of human mesenchymal stem cells
KD Lee, TKC Kuo, J Whang‐Peng, YF Chung… - …, 2004 - Wiley Online Library
This study examined whether mesenchymal stem cells (MSCs), which are stem cells
originated from embryonic mesoderm, are able to differentiate into functional hepatocyte …
originated from embryonic mesoderm, are able to differentiate into functional hepatocyte …
Engineering principles of clinical cell-based tissue engineering
GF Muschler, C Nakamoto, LG Griffith - JBJS, 2004 - journals.lww.com
Tissue engineering is a rapidly evolving discipline that seeks to repair, replace, or
regenerate specific tissues or organs by translating fundamental knowledge in physics …
regenerate specific tissues or organs by translating fundamental knowledge in physics …
Matrix cells from Wharton's jelly form neurons and glia
KE Mitchell, ML Weiss, BM Mitchell, P Martin… - Stem …, 2003 - academic.oup.com
We have identified an easily attainable source of primitive, potentially multipotent stem cells
from Wharton's jelly, the matrix of umbilical cord. Wharton's jelly cells have been propagated …
from Wharton's jelly, the matrix of umbilical cord. Wharton's jelly cells have been propagated …
[HTML][HTML] Rethinking differentiation: stem cells, regeneration, and plasticity
AS Alvarado, S Yamanaka - Cell, 2014 - cell.com
Cell differentiation is an essential process for the development, growth, reproduction, and
longevity of all multicellular organisms, and its regulation has been the focus of intense …
longevity of all multicellular organisms, and its regulation has been the focus of intense …
Stem cells and liver regeneration
One of the defining features of the liver is the capacity to maintain a constant size despite
injury. Although the precise molecular signals involved in the maintenance of liver size are …
injury. Although the precise molecular signals involved in the maintenance of liver size are …
Hypoxia inhibits senescence and maintains mesenchymal stem cell properties through down-regulation of E2A-p21 by HIF-TWIST
CC Tsai, YJ Chen, TL Yew, LL Chen… - Blood, The Journal …, 2011 - ashpublications.org
Although low-density culture provides an efficient method for rapid expansion of human
mesenchymal stem cells (MSCs), MSCs enriched by this method undergo senescence and …
mesenchymal stem cells (MSCs), MSCs enriched by this method undergo senescence and …