Fueled by aging populations and continued environmental contamination, the global burden
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …

Many complex traits or diseases, such as infectious and autoimmune diseases, cancer,
xenobiotics exposure, neurodevelopmental and neurodegenerative diseases, as well as the …

Dapagliflozin, a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor, has emerged
as a promising neuroprotective agent in murine models of epilepsy and obesity-induced …

Introduction: China has the most people with Parkinson disease (PD) in the world and is
estimated to have over half of the worldwide PD population. The objective of this study was …

LRRK2 has been implicated in endolysosomal function and likely plays a central role in
idiopathic Parkinson's disease (iPD). In iPD, dopaminergic neurons within the substantia …

Background: Parkinson's disease (PD) is the second most common neurodegenerative
disorder after Alzheimer's disease and gender differences have been described on several …

Gene-environment interaction is implicated in the majority of idiopathic Parkinson's disease
(PD) risk, and some of the most widespread environmental contaminants are selectively …

Parkinson's disease (PD) is a debilitating neurodegenerative disorder caused by the loss of
midbrain dopamine (DA) neurons. While the cause of DA cell loss in PD is unknown, male …

Individuals with Parkinson's disease (PD) typically receive a diagnosis once they have
developed motor symptoms, at which point there is already significant loss of substantia …

Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease. Inflammation has been observed in both the idiopathic and familial …