Tumor hypoxia is a well-established biological phenomenon that affects the curability of
solid tumors, regardless of treatment modality. Especially for head and neck cancer patients …

In tumours, hypoxia—a condition in which the demand for oxygen is higher than its
availability—is well known to be associated with reduced sensitivity to radiotherapy and …

Osteopontin (OPN) is a matricellular protein that binds to a number of cell surface receptors
including integrins and CD44. It is expressed in many tissues and secreted into body fluids …

A DNA aptamer with affinity and specificity for human osteopontin (OPN), a potential breast
cancer biomarker, was selected using the SELEX process, considering its homology rate …

Background Inflammation can promote tumor growth, invasion, angiogenesis and even
metastasis. Inflammatory markers have been identified as prognostic indicators in various …

The poor prognosis of glioblastoma multiforme (GBM) is primarily due to highly invasive
glioma stem-like cells (GSCs) in tumors. Upon GBM recurrence, GSCs with highly invasive …

The rapid determination of human osteopontin (OPN) protein, a potential cancer biomarker,
holds substantial promise for point-of-care diagnostics and biomedical applications. To date …

Simple Summary 5-ALA Fluorescence Guided Surgery aims at extending the boundaries of
glioblastoma (GBM) resection. It is based on the use of a fluorescent dye, 5-aminolevulinic …

Introduction: Cancer is an extremely complex disease and most cancer treatments are
limited to chemotherapy, radiation and surgery. The progression of tumours towards …

In the current study, we emphasize that osteopontin is overexpressed in oral squamous cell
carcinoma. Overexpression of osteopontin levels was confirmed by mRNA quantification …