The immune system is highly time-of-day dependent. Pioneering studies in the 1960s were
the first to identify immune responses to be under a circadian control. Only in the last …

The term social jetlag is used to describe the discrepancy between biological time,
determined by our internal body clock, and social times, mainly dictated by social obligations …

Cellular senescence is a state of irreversible cell cycle arrest associated with ageing.
Senescence of different cardiac cell types can direct the pathophysiology of cardiovascular …

Objective To develop and present consensus findings of the National Sleep Foundation
sleep timing and variability panel regarding the impact of sleep timing variability on health …

Cellular circadian clocks direct a daily transcriptional program that supports homeostasis
and resilience. Emerging evidence has demonstrated age-associated changes in circadian …

The immune system is built to counteract unpredictable threats, yet it relies on predictable
cycles of activity to function properly. Daily rhythms in immune function are an expanding …

Circadian gene expression is fundamental to the establishment and functions of the
circadian clock, a cell-autonomous and evolutionary-conserved timing system. Yet, how it is …

Circadian rhythms control almost all aspects of physiology and behavior, allowing temporal
synchrony of these processes between each other, as well as with the external environment …

The circadian clock temporally organizes cellular physiology throughout the day, allowing
daily environmental changes to be anticipated and potentially harmful physiologic …

Circadian clocks control the internal sleep-wake rhythmicity of 24 h which is synchronized by
the solar cycle. Circadian regulation of metabolism evolved about 2.5 billion years ago, ie …