Human adenoviruses (HAdV) are ubiquitous human pathogens that cause a significant
burden of respiratory, ocular, and gastrointestinal illnesses. Although HAdV infections are …

A growing interest in pharmacology has made heterocyclic chemistry as one of the emerging
branches of organic chemistry. Piperazine is an excellent heterocycle that possesses a large …

NHC-catalyzed diastereoselective and enantioselective [12+ 2] higher-order cycloadditions
of 5H-benzo [a]-pyrrolizine-3-carbaldehydes with cyclic sulfonic imines are described …

The repositioning of drugs already approved by regulatory agencies for other indications is
an emerging alternative for the development of new antimicrobial therapies. The …

The effective treatment of adenovirus (HAdV) infections in immunocompromised patients still
poses great challenges. Herein, we reported our continued efforts to optimize a series of …

The symptoms of human adenovirus infections are generally mild and self-limiting. However,
these infections have been gaining importance in recent years because of a growing …

Human adenovirus (HAdV) is a very common pathogen that typically causes minor disease
in most patients. However, the virus can cause significant morbidity and mortality in certain …

Highlights•Adenovirus infections in immunosuppressed patients.•Drug discovery against
adenovirus.•Screening and evaluation methodologies for drug discovery.•Viral and host …

In recent years, human adenovirus (HAdV) infections have shown a high clinical impact in
both immunosuppressed and immunocompetent patients. The research into specific antiviral …

Human adenovirus (HAdV) is a common pathogen that can cause severe morbidity and
mortality in certain populations, including pediatric, geriatric, and immunocompromised …