[HTML][HTML] The application of brain organoids: from neuronal development to neurological diseases
Y Shou, F Liang, S Xu, X Li - Frontiers in cell and developmental …, 2020 - frontiersin.org
Brain organoids are derived from induced pluripotent stem cells and embryonic stem cells
under 3-dimensional culture condition. The generation of organoid requires the self …
under 3-dimensional culture condition. The generation of organoid requires the self …
Revolutionizing disease Modeling: the emergence of organoids in cellular systems
R Silva-Pedrosa, AJ Salgado, PE Ferreira - Cells, 2023 - mdpi.com
Cellular models have created opportunities to explore the characteristics of human diseases
through well-established protocols, while avoiding the ethical restrictions associated with …
through well-established protocols, while avoiding the ethical restrictions associated with …
Neuronal cell life, death, and axonal degeneration as regulated by the BCL-2 family proteins
JM Pemberton, JP Pogmore, DW Andrews - Cell Death & Differentiation, 2021 - nature.com
Axonal degeneration and neuronal cell death are fundamental processes in development
and contribute to the pathology of neurological disease in adults. Both processes are …
and contribute to the pathology of neurological disease in adults. Both processes are …
Global Meta-Analysis of Organoid and Organ-on-Chip Research.
J Shoji, RP Davis, CL Mummery… - Advanced healthcare …, 2023 - duo.uio.no
Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical,
physiological, or pathological states of tissues and organs. These technologies are widely …
physiological, or pathological states of tissues and organs. These technologies are widely …
Human 3D brain organoids: steering the demolecularization of brain and neurological diseases
YK Adlakha - Cell Death Discovery, 2023 - nature.com
Understanding of human brain development, dysfunction and neurological diseases has
remained limited and challenging due to inability to recapitulate human brain-specific …
remained limited and challenging due to inability to recapitulate human brain-specific …
Cerebral Malaria and Neuronal Implications of Plasmodium Falciparum Infection: From Mechanisms to Advanced Models
Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum
enables their sequestration via attachment to the microvasculature. This artificially increases …
enables their sequestration via attachment to the microvasculature. This artificially increases …
Modeling neurodegenerative diseases with cerebral organoids and other three-dimensional culture systems: Focus on Alzheimer's disease
Many neurodegenerative diseases (NDs) such as Alzheimer's disease, Parkinson's disease,
frontotemporal dementia, amyotrophic lateral sclerosis and Huntington's disease, are …
frontotemporal dementia, amyotrophic lateral sclerosis and Huntington's disease, are …
Human pluripotent stem cell (hPSC) and organoid models of autism: opportunities and limitations
S Kilpatrick, C Irwin, KK Singh - Translational Psychiatry, 2023 - nature.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder caused by
genetic or environmental perturbations during early development. Diagnoses are dependent …
genetic or environmental perturbations during early development. Diagnoses are dependent …
Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8+ T cells
J Liang, Y Shen, Y Wang, Y Huang, J Wang, Q Zhu… - Molecular Brain, 2022 - Springer
Cerebral malaria is the most serious complication of malaria infection, with 26% of surviving
children having neurological sequelae, which may be caused by neuron damage, but the …
children having neurological sequelae, which may be caused by neuron damage, but the …
Transcending Dimensions in Apicomplexan Research: from Two-Dimensional to Three-Dimensional In Vitro Cultures
CJ Ramírez-Flores… - Microbiology and …, 2022 - Am Soc Microbiol
Parasites belonging to the Apicomplexa phylum are among the most successful pathogens
known in nature. They can infect a wide range of hosts, often remain undetected by the …
known in nature. They can infect a wide range of hosts, often remain undetected by the …