Aggressive and recurrent gynecological cancers are associated with worse prognosis and a
lack of effective therapeutic response. Ovarian cancer (OC) patients are often diagnosed in …

Background CA-125 is a clinical biomarker with predictive effect on the prognosis of different
cancers. Numerous clinical trials have been conducted to investigate the possibility of using …

Ovarian cancer is mostly diagnosed at advantaged stages due to the lack of early diagnostic
biomarkers. The common metastasis pattern is characterized by peritoneal dissemination …

A global protein interactome ensures the maintenance of regulatory, signaling and structural
processes in cells, but at the same time, aberrations in the repertoire of protein–protein …

Ovarian cancer is one of the most lethal female cancers. For accurate prognosis prediction,
this study aimed to investigate novel, blood-based prognostic biomarkers for high-grade …

Fatty acid metabolism, including β-oxidation (βOX), plays an important role in human
physiology and pathology. βOX is an essential process in the energy metabolism of most …

Lgr5 has been identified as a marker of the stem/progenitor cells in the murine ovary and
oviduct by lineage tracing. However, little is known regarding LGR5 expression or its …

Abstract The microRNA (miR) miR-874, a potential tumour suppressor, causes cell death via
target gene suppression in various cancer types. Mevalonate pathway inhibition also causes …

Tumor infiltrating mast cells (TIMs), with pro-or anti-tumorigenic role in different types of
malignancies, have been implicated in resistance to anti-PD1 therapy. Here, we aimed to …

Background. Stomach adenocarcinoma (STAD) is a common malignancy worldwide with
poor prognosis. Therefore, it is important to identify a valuable prognostic biomarker for …