[HTML][HTML] Deregulated PTEN/PI3K/AKT/mTOR signaling in prostate cancer: still a potential druggable target?
L Braglia, M Zavatti, M Vinceti, AM Martelli… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Although the prognosis of patients with localized prostate cancer is good after surgery, with
a favorable response to androgen deprivation therapy, about one third of them invariably …
a favorable response to androgen deprivation therapy, about one third of them invariably …
Exposure to an environmentally relevant phthalate mixture during prostate development induces microRNA upregulation and transcriptome modulation in rats
WR Scarano, A Bedrat, LG Alonso-Costa… - Toxicological …, 2019 - academic.oup.com
Environmental exposure to phthalates during intrauterine development might increase
susceptibility to neoplasms in reproductive organs such as the prostate. Although studies …
susceptibility to neoplasms in reproductive organs such as the prostate. Although studies …
The PI3K/mTOR dual inhibitor BEZ235 nanoparticles improve radiosensitization of hepatoma cells through apoptosis and regulation DNA repair pathway
X Tang, A Li, C Xie, Y Zhang, X Liu, Y Xie, B Wu… - Nanoscale research …, 2020 - Springer
Polymer materials encapsulating drugs have broad prospects for drug delivery. We
evaluated the effectiveness of polyethylene glycol-poly (lactic-co-glycolic acid)(PLGA-PEG) …
evaluated the effectiveness of polyethylene glycol-poly (lactic-co-glycolic acid)(PLGA-PEG) …
Bloom syndrome protein activates AKT and PRAS40 in prostate cancer cells
K Chen, H Xu, J Zhao - Oxidative Medicine and Cellular …, 2019 - Wiley Online Library
Purpose. Prostate cancer (PC) is a common malignant tumor and a leading cause of cancer‐
related death in men worldwide. In order to design new therapeutic interventions for PC, an …
related death in men worldwide. In order to design new therapeutic interventions for PC, an …
Herb–drug interactions between androgenic Chinese herbal medicines and androgen receptor antagonist on tumor growth: Studies on two xenograft prostate cancer …
Our previous study revealed that Epimedii Folium (EF) and Codonopsis Radix (CNR)
significantly promoted tumor growth on a subcutaneous mouse model of prostate cancer …
significantly promoted tumor growth on a subcutaneous mouse model of prostate cancer …
Development of a Robust Synthesis of Dactolisib on a Commercial Manufacturing Scale
M Baenziger, W Pachinger, F Stauffer… - … Process Research & …, 2019 - ACS Publications
The development of the robust synthesis of 2-methyl-2-[4-[3-methyl-2-oxo-8-(quinolin-3-yl)-
2, 3-dihydro-1 H-imidazo [4, 5-c] quinolin-1-yl]-phenyl] propionitrile (dactolisib) on a …
2, 3-dihydro-1 H-imidazo [4, 5-c] quinolin-1-yl]-phenyl] propionitrile (dactolisib) on a …