[HTML][HTML] Long COVID: the nature of thrombotic sequelae determines the necessity of early anticoagulation

C Wang, C Yu, H Jing, X Wu, VA Novakovic… - Frontiers in Cellular …, 2022 - frontiersin.org
Many discharged COVID-19 patients affected by sequelae experience reduced quality of life
leading to an increased burden on the healthcare system, their families and society at large …

The pulmonary pathology of COVID-19

H Bösmüller, M Matter, F Fend, A Tzankov - Virchows Archiv, 2021 - Springer
The lung is the main affected organ in severe coronavirus disease 2019 (COVID-19) caused
by the novel coronavirus SARS-CoV-2, and lung damage is the leading cause of death in …

[HTML][HTML] Management of hospitalised adults with coronavirus disease 2019 (COVID-19): a European Respiratory Society living guideline

JD Chalmers, ML Crichton… - European respiratory …, 2021 - Eur Respiratory Soc
Introduction Hospitalised patients with coronavirus disease 2019 (COVID-19) as a result of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have a high …

Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation

FWJ Chioh, SW Fong, BE Young, KX Wu, A Siau… - Elife, 2021 - elifesciences.org
Numerous reports of vascular events after an initial recovery from COVID-19 form our
impetus to investigate the impact of COVID-19 on vascular health of recovered patients. We …

Exercise ventilatory inefficiency in post-COVID-19 syndrome: insights from a prospective evaluation

Á Aparisi, C Ybarra-Falcón, M García-Gómez… - Journal of Clinical …, 2021 - mdpi.com
Introduction: Coronavirus disease 2019 (COVID-19) is a systemic disease characterized by
a disproportionate inflammatory response in the acute phase. This study sought to identify …

Update June 2022: management of hospitalised adults with coronavirus disease 2019 (COVID-19): a European Respiratory Society living guideline

N Roche, ML Crichton, PC Goeminne… - European respiratory …, 2022 - Eur Respiratory Soc
Since the identification of SARS-CoV-2 at the end of 2019, the coronavirus disease 2019
(COVID-19) pandemic has affected more than 410 million people worldwide and killed …

Endothelial cell plasticity at the single-cell level

A Pasut, LM Becker, A Cuypers, P Carmeliet - Angiogenesis, 2021 - Springer
The vascular endothelium is characterized by a remarkable level of plasticity, which is the
driving force not only of physiological repair/remodeling of adult tissues but also of …

SARS-CoV-2 brain regional detection, histopathology, gene expression, and immunomodulatory changes in decedents with COVID-19

GE Serrano, JE Walker, C Tremblay… - … of Neuropathology & …, 2022 - academic.oup.com
Brains of 42 COVID-19 decedents and 107 non-COVID-19 controls were studied. RT-PCR
screening of 16 regions from 20 COVID-19 autopsies found SARS-CoV-2 E gene viral …

The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling

M Ackermann, JC Kamp, C Werlein, CL Walsh… - …, 2022 - thelancet.com
Background COVID-19 is characterized by a heterogeneous clinical presentation, ranging
from mild symptoms to severe courses of disease. 9–20% of hospitalized patients with …

Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review

A Shafqat, S Shafqat, SA Salameh, J Kashir… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …