The potential of tailoring the gut microbiome to prevent and treat cardiometabolic disease

RM Chakaroun, LM Olsson, F Bäckhed - Nature Reviews Cardiology, 2023 - nature.com
Despite milestones in preventive measures and treatment, cardiovascular disease (CVD)
remains associated with a high burden of morbidity and mortality. The protracted nature of …

Novel methods for pulse wave velocity measurement

T Pereira, C Correia, J Cardoso - Journal of medical and biological …, 2015 - Springer
The great incidence of cardiovascular (CV) diseases in the world spurs the search for new
solutions to enable an early detection of pathological processes and provides more precise …

Gut microbial diversity is associated with lower arterial stiffness in women

C Menni, C Lin, M Cecelja, M Mangino… - European Heart …, 2018 - academic.oup.com
Aims The gut microbiome influences metabolic syndrome (MetS) and inflammation and is
therapeutically modifiable. Arterial stiffness is poorly correlated with most traditional risk …

Gut microbiota in hypertension

PA Jose, D Raj - Current opinion in nephrology and hypertension, 2015 - journals.lww.com
Gut microbiota in hypertension : Current Opinion in Nephrology and Hypertension Gut
microbiota in hypertension : Current Opinion in Nephrology and Hypertension Log in or …

Gut-microbiota-metabolite axis in early renal function decline

C Barrios, M Beaumont, T Pallister, J Villar… - PloS one, 2015 - journals.plos.org
Introduction Several circulating metabolites derived from bacterial protein fermentation have
been found to be inversely associated with renal function but the timing and disease severity …

The gut microbiota-related metabolite phenylacetylglutamine associates with increased risk of incident coronary artery disease

F Ottosson, L Brunkwall, E Smith… - Journal of …, 2020 - journals.lww.com
Objective: The gut microbiota is increasingly being implicated in cardiovascular health.
Metabolites produced by bacteria have been suggested to be mediators in the bacterial …

Towards precision medicine for hypertension: a review of genomic, epigenomic, and microbiomic effects on blood pressure in experimental rat models and humans

S Padmanabhan, B Joe - Physiological reviews, 2017 - journals.physiology.org
Compelling evidence for the inherited nature of essential hypertension has led to extensive
research in rats and humans. Rats have served as the primary model for research on the …

Hypertension as an autoimmune and inflammatory disease

Y Solak, B Afsar, ND Vaziri, G Aslan, CE Yalcin… - Hypertension …, 2016 - nature.com
Hypertension that is considered idiopathic is called essential hypertension and accordingly
has no clear culprit for its cause. However, basic research and clinical studies in recent …

Phenylacetylglutamine, a novel biomarker in acute ischemic stroke

F Yu, X Li, X Feng, M Wei, Y Luo, T Zhao… - Frontiers in …, 2021 - frontiersin.org
Background: To discover novel metabolic biomarkers of ischemic stroke (IS), we carried out
a two-stage metabolomic profiling of IS patients and healthy controls using untargeted and …

[HTML][HTML] Investigating causal associations among gut microbiota, gut microbiota-derived metabolites, and gestational diabetes mellitus: a bidirectional Mendelian …

X Wu, D Lin, Q Li, J Cai, H Huang, T Xiang… - Aging (Albany NY …, 2023 - ncbi.nlm.nih.gov
Background: Previous studies have shown that gut microbiota (GM) and gut microbiota-
derived metabolites are associated with gestational diabetes mellitus (GDM). However, the …