Abstract Type 2 diabetes (T2D) is a very prevalent, multisystemic, chronic metabolic disorder
closely related to atherosclerosis and cardiovascular diseases. It is characterised by …

Diabetes is accompanied by several complications. Higher prevalence of cancers,
cardiovascular diseases, chronic kidney disease (CKD), obesity, osteoporosis, and …

Increased evidence shows that gut microbiota acts as the primary regulator of the liver;
however, its role in sepsis-related liver injury (SLI) in the elderly is unclear. This study …

The novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is currently the biggest threat to the public health …

Critically ill, severely injured and high-risk surgical patients are vulnerable to secondary
infections during hospitalization and after hospital discharge. Studies show that the …

Metformin, the first choice drug for type 2 diabetes treatment in all stages of therapy, and one
of the most widely prescribed anti-hyperglycemic agents worldwide, represents a rare …

Treatments that target single mediators of sepsis have failed to reduce its high mortality rate.
Here we developed multifunctional tannic acid-Zn 2+-gentamicin nanoparticles (TA-Zn-Gen …

Background Recent evidence indicates that metformin inhibits mammalian cancer growth
and metastasis through the regulation of microRNAs. Metformin regulates miR-381 stability …

Since the outbreak of Covid-19, several observational studies on diabetes and Covid-19
have reported a favourable association between metformin and Covid-19-related outcomes …

Acute central nervous system injuries (ACNSI), encompassing traumatic brain injury (TBI),
non-traumatic brain injury like stroke and encephalomeningitis, as well as spinal cord …