Abstract Purpose of the Review Buruli ulcer (BU) is a necrotizing and disabling cutaneous
disease caused by Mycobacterium ulcerans, one of the skin-related neglected tropical …

Bacterial toxins are virulence factors that manipulate host cell functions and take over the
control of vital processes of living organisms to favor microbial infection. Some toxins directly …

Mycobacterium ulcerans, the etiological agent of Buruli ulcer, causes extensive skin lesions,
which despite their severity are not accompanied by pain. It was previously thought that this …

Infection with Mycobacterium ulcerans is characterised by tissue necrosis and
immunosuppression due to mycolactone, the necessary and sufficient virulence factor for …

Mycolactone, an immunosuppressive macrolide released by the human pathogen
Mycobacterium ulcerans, was previously shown to impair Sec61-dependent protein …

Abstract Purpose of Review This review describes recent trends in the epidemiology of
nontuberculous mycobacteria (NTM), emerging pathogens, new insights into NTM …

Infection with Mycobacterium ulcerans results in a necrotising skin disease known as a
Buruli ulcer, the pathology of which is directly linked to the bacterial production of the toxin …

Buruli ulcer is a noncontagious disabling cutaneous and subcutaneous mycobacteriosis
reported by 33 countries in Africa, Asia, Oceania, and South America. The causative agent …

Infection of subcutaneous tissue with Mycobacterium ulcerans can lead to chronic skin
ulceration known as Buruli ulcer. The pathogenesis of this neglected tropical disease is …

The virulence factor mycolactone is responsible for the immunosuppression and tissue
necrosis that characterise Buruli ulcer, a disease caused by infection with Mycobacterium …