Effects of mineralization on the hierarchical organization of collagen—a synchrotron X-ray scattering and polarized second harmonic generation study
The process of mineralization fundamentally alters collagenous tissue biomechanics. While
the structure and organization of mineral particles have been widely studied, the impact of …
the structure and organization of mineral particles have been widely studied, the impact of …
[HTML][HTML] Combining polarized Raman spectroscopy and micropillar compression to study microscale structure-property relationships in mineralized tissues
Bone is a natural composite possessing outstanding mechanical properties combined with a
lightweight design. The key feature contributing to this unusual combination of properties is …
lightweight design. The key feature contributing to this unusual combination of properties is …
Three-dimensional structural interrelations between cells, extracellular matrix, and mineral in normally mineralizing avian leg tendon
The spatial-temporal relationship between cells, extracellular matrices, and mineral deposits
is fundamental for an improved understanding of mineralization mechanisms in vertebrate …
is fundamental for an improved understanding of mineralization mechanisms in vertebrate …
[HTML][HTML] Structure and collagen crimp patterns of functionally distinct equine tendons, revealed by quantitative polarised light microscopy (qPLM)
Abstract Structure-function relationships in tendons are directly influenced by the
arrangement of collagen fibres. However, the details of such arrangements in functionally …
arrangement of collagen fibres. However, the details of such arrangements in functionally …
Compressive behaviour of uniaxially aligned individual mineralised collagen fibres at the micro-and nanoscale
The increasing incidence of osteoporotic bone fractures makes fracture risk prediction an
important clinical challenge. Computational models can be utilised to facilitate such …
important clinical challenge. Computational models can be utilised to facilitate such …
An efficient two-scale 3D FE model of the bone fibril array: comparison of anisotropic elastic properties with analytical methods and micro-sample testing
E Alizadeh, M Dehestani, P Zysset - Biomechanics and modeling in …, 2020 - Springer
In this study, 3D finite element analyses (FEA) are conducted to quantify the orthotropic
elastic properties and investigate the load transfer mechanism of bone at the sub-lamellar …
elastic properties and investigate the load transfer mechanism of bone at the sub-lamellar …
An experimentally informed statistical elasto-plastic mineralised collagen fibre model at the micrometre and nanometre lengthscale
Bone is an intriguingly complex material. It combines high strength, toughness and
lightweight via an elaborate hierarchical structure. This structure results from a biologically …
lightweight via an elaborate hierarchical structure. This structure results from a biologically …
Understanding the effects of mineralization and structure on the mechanical properties of tendon-bone insertion using mesoscale computational modeling
Tendon-bone fibrocartilaginous insertion, or enthesis, is a specialized interfacial region that
connects tendon and bone, effectively transferring forces while minimizing stress …
connects tendon and bone, effectively transferring forces while minimizing stress …
Assessing the effective elastic properties of the tendon-to-bone insertion: a multiscale modeling approach
The interphase joining tendon to bone plays the crucial role of integrating soft to hard
tissues, by effectively transferring stresses across two tissues displaying a mismatch in …
tissues, by effectively transferring stresses across two tissues displaying a mismatch in …
Single shot quantitative polarized light imaging system for rapid planar biaxial testing of soft tissues
MJ Blair, KP Quinn - Frontiers in Bioengineering and Biotechnology, 2022 - frontiersin.org
Quantitative Polarized Light Imaging (QPLI) is an established technique used to compute the
orientation of collagen fibers based on their birefringence. QPLI systems typically require …
orientation of collagen fibers based on their birefringence. QPLI systems typically require …