[HTML][HTML] From clones to immunopeptidomes: new developments in the characterization of permissive HLA-DP mismatches in hematopoietic cell transplantation

E Arrieta-Bolaños - Best Practice & Research Clinical Haematology, 2024 - Elsevier
Mismatching at the HLA-DPB1 locus occurs frequently in hematopoietic cell transplantation
with unrelated donors. Despite this, HLA-DPB1 allelic mismatches have traditionally not …

Post-transplant cyclophosphamide–based graft-versus-host disease prophylaxis attenuates disparity in outcomes between use of matched or mismatched unrelated …

BC Shaffer, M Gooptu, TE DeFor, M Maiers… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Access to allogeneic hematopoietic cell transplantation (HCT) remains limited
among persons of non-European ancestry if human leukocyte antigen (HLA) matching is …

Providing hematopoietic stem cell products from unrelated donors to the world: DKMS donor centers and DKMS registry

AH Schmidt, J Sauter, J Schetelig, E Neujahr… - Best Practice & …, 2024 - Elsevier
Allogeneic hematopoietic stem cell (HSC) transplantation is a curative therapy for many
severe blood diseases. As many patients have no suitable family donor, large unrelated …

Expanding donor options: haploidentical transplant recipients are also highly likely to have a 7/8-matched unrelated donor

S Fingerson, M Maiers, YT Bolon, SM Devine… - Blood …, 2024 - ashpublications.org
The use of haploidentical related donor (HRD) hematopoietic cell transplants (HCTs) in the
United States grew by more than fourfold in the last decade, driven mainly by use of …

Improving Unrelated Donor Equity: Assessing Mismatched Donor Opportunities with Real-World Data in a Minority-Predominant Cohort

MB Hammami, JA Verceles, M Goldfinger… - … and Cellular Therapy, 2024 - Elsevier
Recent advances in graft-versus-host disease (GVHD) prophylaxis including post-transplant
cyclophosphamide (PTCy) and abatacept have significantly improved outcomes following …

Unrelated hematopoietic stem cell donor registries: present reality and future prospects

AH Schmidt - Current Opinion in Hematology, 2024 - journals.lww.com
The international community of donor registries, together with the World Marrow Donor
Association, has helped many patients in need of a stem cell transplant over the past …

Optimized GVHD Prevention in HLA‐Mismatched Unrelated Allogeneic HCT Using a PTCY‐Based Approach

FR Pinto, M Suárez‐Lledó, L Guardia… - European Journal of …, 2024 - Wiley Online Library
Although post‐transplant cyclophosphamide (PTCY)‐based prophylaxis has become a
widely adopted strategy for preventing graft‐versus‐host disease (GVHD) in 9 out of 10 HLA …

The Evolution of Hematopoietic Stem Cell Transplantation to Overcome Access Disparities: The Role of NMDP

SM Devine - Cells, 2024 - mdpi.com
NMDP recognizes that despite advances in hematopoietic stem cell transplantation (HSCT)
and other cell therapies, not all patients have equitable access to treatment, and disparities …

Donor selection in allogeneic stem cell transplantation

F Barriga, ACM Lima - Current Opinion in Hematology, 2024 - journals.lww.com
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Applying implementation science in the field of transplant and cellular therapy

AM DeSalvo, SR Spellman, JAS Coles, D Robb… - … and Cellular Therapy, 2024 - Elsevier
Implementation science (IS) is a systematic way to approach the broader adoption of
evidence-based practices and has as its goal to understand and address the gap between …