Mechanisms of persistent neurobiological changes following adolescent alcohol exposure: NADIA consortium findings

FT Crews, DL Robinson, LJ Chandler… - Alcoholism: clinical …, 2019 - Wiley Online Library
The Neurobiology of Adolescent Drinking in Adulthood (NADIA) Consortium has focused on
the impact of adolescent binge drinking on brain development, particularly on effects that …

Toll-like receptor signaling and stages of addiction

FT Crews, TJ Walter, LG Coleman, RP Vetreno - Psychopharmacology, 2017 - Springer
Abstract Background Athina Markou and her colleagues discovered persistent changes in
adult behavior following adolescent exposure to ethanol or nicotine consistent with …

Preparation of n-ZnO/p-Co3O4 heterojunctions from zeolitic imidazolate frameworks (ZIF-8/ZIF-67) for sensing low ethanol concentrations

TLH Doan, JY Kim, JH Lee, LHT Nguyen… - Sensors and Actuators B …, 2021 - Elsevier
Nano-heterojunctions of n-ZnO/p-Co 3 O 4 with varying molar ratios of Co 3 O 4 derived from
a zeolitic imidazolate framework (ZIF-8/ZIF-67) were efficiently synthesized and well …

Targeting persistent changes in neuroimmune and epigenetic signaling in adolescent drinking to treat alcohol use disorder in adulthood

FT Crews, LG Coleman Jr, VA Macht, RP Vetreno… - Pharmacological …, 2023 - Elsevier
Studies universally find early age of drinking onset is linked to lifelong risks of alcohol
problems and alcohol use disorder (AUD). Assessment of the lasting effect of drinking during …

Neuropeptide system regulation of prefrontal cortex circuitry: implications for neuropsychiatric disorders

SM Casello, RJ Flores, HE Yarur, H Wang… - Frontiers in Neural …, 2022 - frontiersin.org
Neuropeptides, a diverse class of signaling molecules in the nervous system, modulate
various biological effects including membrane excitability, synaptic transmission and …

Regulatory pathways of monoamine oxidase A during social stress

Y Higuchi, T Soga, IS Parhar - Frontiers in Neuroscience, 2017 - frontiersin.org
Social stress has a high impact on many biological systems in the brain, including
serotonergic (5-HT) system—a major drug target in the current treatment for depression …

Turning the′ Tides on neuropsychiatric diseases: the role of peptides in the prefrontal cortex

DF Brockway, NA Crowley - Frontiers in Behavioral Neuroscience, 2020 - frontiersin.org
Recent advancements in technology have enabled researchers to probe the brain with the
greater region, cell, and receptor specificity. These developments have allowed for a more …

Individual decision-making in the causal pathway to addiction: contributions and limitations of rodent models

SH Ahmed - Pharmacology Biochemistry and Behavior, 2018 - Elsevier
The causal pathway from vulnerability to drug use and addiction involves a complex
interaction between genetic, environmental, and behavioral factors. An individual can …

Adolescent intermittent ethanol exposure enhances adult stress effects in male rats

KL Healey, S Kibble, K Dubester, A Bell… - Pharmacology …, 2023 - Elsevier
Binge patterns of alcohol use, prevalent among adolescents, are associated with a higher
probability of developing alcohol use disorders (AUD) and other psychiatric disorders, like …

Biological intersection of sex, age, and environment in the corticotropin releasing factor (CRF) system and alcohol

AE Agoglia, EJ Crofton, MA Herman - Neuropharmacology, 2020 - Elsevier
The neuropeptide corticotropin-releasing factor (CRF) is critical in neural circuit function and
behavior, particularly in the context of stress, anxiety, and addiction. Despite a wealth of …