Autophagy is an evolutionarily conserved catabolic cellular process that exerts antiviral
functions during a viral invasion. However, co-evolution and co-adaptation between viruses …

Coronaviruses (CoVs) are members of the genus Betacoronavirus and the Coronaviridiae
family responsible for infections such as severe acute respiratory syndrome (SARS), Middle …

Aberrant activation of NLRP3 inflammasome in colonic macrophages strongly associates
with the occurrence and progression of ulcerative colitis. Although targeting NLRP3 …

Parasitic nematodes have an intimate, chronic and lifelong exposure to vertebrate tissues.
Here we mined 41 published parasitic nematode transcriptomes from vertebrate hosts and …

Leishmania are protozoan parasites that predominantly reside in myeloid cells within their
mammalian hosts. Monocytes and macrophages play a central role in the pathogenesis of …

Cell death is an essential immunological apparatus of host defense, but dysregulation of
mutually inclusive cell deaths poses severe threats during microbial and parasitic infections …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces mild or
asymptomatic COVID-19 in most cases, but some patients develop an excessive …

Viruses are the most abundant biological entities on Earth and play a significant role in the
evolution of many organisms and ecosystems. In pathogenic protozoa, the presence of …

Intracellular parasites from the Leishmania genus cause Leishmaniasis, a disease affecting
millions of people worldwide. NLRP3 inflammasome is key for disease outcome, but the …

Cutaneous leishmaniasis (CL) is a significant public health problem caused by different
species of Leishmania parasites. Due to low skin permeability, the development of an …