Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance

M Xu, Y Qi, G Liu, Y Song, X Jiang, B Du - ACS nano, 2023 - ACS Publications
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …

From femtoseconds to hours—measuring dynamics over 18 orders of magnitude with coherent x-rays

F Lehmkühler, W Roseker, G Grübel - Applied Sciences, 2021 - mdpi.com
X-ray photon correlation spectroscopy (XPCS) enables the study of sample dynamics
between micrometer and atomic length scales. As a coherent scattering technique, it …

Design of disintegrable nanoassemblies to release multiple small-sized nanoparticles

D Zhu, H Yan, Y Zhou, LM Nack, J Liu… - Advanced Drug Delivery …, 2023 - Elsevier
The therapeutic and diagnostic effects of nanoparticles highly depend on the efficiency of
their delivery to targeted tissues, such as tumors. The size of nanoparticles, among other …

In situ label-free X-ray imaging for visualizing the localization of nanomedicines and subcellular architecture in intact single cells

M Cao, Y Wang, L Wang, K Zhang, Y Guan, Y Guo… - Nature …, 2024 - nature.com
Understanding the intracellular behaviors of nanomedicines and morphology variation of
subcellular architecture impacted by nanomaterial–biology (nano–bio) interactions could …

A comparative study of ultrasmall calcium carbonate nanoparticles for targeting and imaging atherosclerotic plaque

L Martínez-Parra, M Piñol-Cancer, C Sanchez-Cano… - ACS …, 2023 - ACS Publications
Atherosclerosis is a complex disease that can lead to life-threatening events, such as
myocardial infarction and ischemic stroke. Despite the severity of this disease, diagnosing …

Ptychography at the carbon K-edge

N Mille, H Yuan, J Vijayakumar, S Stanescu… - Communications …, 2022 - nature.com
Ptychography is a coherent diffraction imaging technique that measures diffraction patterns
at many overlapping points on a sample and then uses an algorithm to reconstruct …

Enabling X-ray fluorescence imaging for in vivo immune cell tracking

T Staufer, C Körnig, B Liu, Y Liu, C Lanzloth… - Scientific Reports, 2023 - nature.com
The infiltration of immune cells into sites of inflammation is one key feature of immune
mediated inflammatory diseases. A detailed assessment of the in vivo dynamics of relevant …

A chirality-based quantum leap

CD Aiello, JM Abendroth, M Abbas, A Afanasev… - ACS …, 2022 - ACS Publications
There is increasing interest in the study of chiral degrees of freedom occurring in matter and
in electromagnetic fields. Opportunities in quantum sciences will likely exploit two main …

Synchrotron X-ray studies of the structural and functional hierarchies in mineralised human dental enamel: A state-of-the-art review

C Besnard, A Marie, S Sasidharan, RA Harper… - Dentistry Journal, 2023 - mdpi.com
Hard dental tissues possess a complex hierarchical structure that is particularly evident in
enamel, the most mineralised substance in the human body. Its complex and interlinked …

Advanced light source analytical techniques for exploring the biological behavior and fate of nanomedicines

M Cao, K Zhang, S Zhang, Y Wang… - ACS Central Science, 2022 - ACS Publications
Exploration of the biological behavior and fate of nanoparticles, as affected by the
nanomaterial–biology (nano–bio) interaction, has become progressively critical for guiding …