Application of PLGA as a biodegradable and biocompatible polymer for pulmonary delivery of drugs

R Mahar, A Chakraborty, N Nainwal, R Bahuguna… - Aaps Pharmscitech, 2023 - Springer
Pulmonary administration of biodegradable polymeric formulation is beneficial in the
treatment of various respiratory diseases. For respiratory delivery, the polymer must be non …

Inhalable nanoparticle-based dry powder formulations for respiratory diseases: challenges and strategies for translational research

HW Chan, S Chow, X Zhang, Y Zhao, HHY Tong… - AAPS …, 2023 - Springer
The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …

The future of poly (2-oxazoline) s

R Hoogenboom - European Polymer Journal, 2022 - Elsevier
Abstract Poly (2-oxazoline) s have gained significant interest in the past decade, especially
driven by their high potential for biomedical applications, amongst others to substitute poly …

Inhalation drug delivery in combating pulmonary infections: Advances and challenges

P Kumbhar, J Kaur, G De Rubis, KR Paudel… - Journal of Drug Delivery …, 2023 - Elsevier
Pulmonary infections (PIs) are contributing as a significant cause of mortality across the
world. The clinical applications of a variety of therapeutics approved for PIs have been …

Antibiotic loaded inhalable liposomal nanoparticles against lower respiratory tract infections: Challenges, recent advances, and future perspectives

VK Panthi, KE Fairfull-Smith, N Islam - Journal of Drug Delivery Science …, 2024 - Elsevier
Lower respiratory tract infections (LRTIs) are inherited disorders which often causes chronic
respiratory infections for which patients repeatedly receive oral antibiotics, particularly …

Cytotoxic and bactericidal effects of inhalable ciprofloxacin-loaded poly (2-ethyl-2-oxazoline) nanoparticles with traces of zinc oxide

MZR Sabuj, F Huygens, KM Spann, AA Tarique… - International Journal of …, 2023 - mdpi.com
The bactericidal effects of inhalable ciprofloxacin (CIP) loaded-poly (2-ethyl-2-
oxazoline)(PEtOx) nanoparticles (NPs) with traces of zinc oxide (ZnO) were investigated …

[HTML][HTML] Biomaterial therapeutic strategies for treatment of bacterial lung infections

E Chee, AJ García - Biofilm, 2023 - Elsevier
Bacterial infections of the lung frequently occur as a secondary infection to many respiratory
viral infections and conditions, including influenza, COVID-19, chronic obstructive …

Impact of leucine and magnesium stearate on the physicochemical properties and aerosolization behavior of wet milled inhalable ibuprofen microparticles for …

S Sharif, S Muneer, EL Izake, N Islam - Pharmaceutics, 2023 - mdpi.com
This study investigated the development and characterization of leucine and magnesium
stearate (MgSt) embedded wet milled inhalable ibuprofen (IBF) dry powder inhaler (DPI) …

Inhaled ivermectin-loaded lipid polymer hybrid nanoparticles: development and characterization

SN Kassaee, GA Ayoko, D Richard, T Wang… - …, 2024 - pmc.ncbi.nlm.nih.gov
Ivermectin (IVM), a drug originally used for treating parasitic infections, is being explored for
its potential applications in cancer therapy. Despite the promising anti-cancer effects of IVM …

Robust Wet Milling Technique for Producing Micronized Ibuprofen Particles with Improved Solubility and Dissolution

S Sharif, S Muneer, T Wang, EL Izake, N Islam - AAPS PharmSciTech, 2022 - Springer
This study investigated a systematic approach for producing ibuprofen (IBF) particles with
leucine by wet milling. Using a high shear homogenizer, the particles size of the IBF was …