Adolescence is the peak period for the incidence of anxiety disorders. Recent findings have
revealed the immaturity of neural networks underlying emotional regulation in this …

Anxiety disorders that develop in adolescence represent a significant burden and are
particularly challenging to treat, due in no small part to the high occurrence of relapse in this …

Chronic pain can cause both hyperalgesia and anxiety symptoms. However, how the two
components are encoded in the brain remains unclear. The prelimbic cortex (PrL), a critical …

Adolescence is a time of significant neurocognitive development. Prolonged maturation of
prefrontal cortex (PFC) through adolescence has been found to support improvements in …

Anxiety and fear-related disorders peak in prevalence during adolescence, a window of
rapid behavioral development and neural remodeling. However, understanding of the …

Elevations in glucocorticoids that result from environmental stressors can have programming
effects on brain structure and function when the exposure occurs during sensitive periods …

Chronic stress‐related psychiatric diseases, such as major depression, posttraumatic stress
disorder, and schizophrenia, are characterized by a maladaptive organization of behavioral …

Stress can negatively impact brain function and behaviors across the lifespan. However,
stressors during adolescence have particularly harmful effects on brain maturation, and on …

Adolescence is considered a developmental period of heightened vulnerability to many
psychological dysfunctions–primarily due to the high structural neuronal plasticity that …

Neuroplasticity may be defined as the ability of the central nervous system (CNS) to respond
to changes in the internal and external environment and it is well established that some …