The brain is expensive, incurring high material and metabolic costs for its size—relative to
the size of the body—and many aspects of brain network organization can be mostly …

We introduce comparative connectomics, the quantitative study of cross-species
commonalities and variations in brain network topology that aims to discover general …

Deciphering how neuronal diversity is established and maintained requires a detailed
knowledge of neuronal gene expression throughout development. In contrast to mammalian …

Complex systems, composed at the most basic level of units and their interactions, describe
phenomena in a wide variety of domains, from neuroscience to computer science and …

Precise patterns of synaptic connections between neurons are encoded in their genetic
programs. Here, we use single-cell RNA sequencing to profile neuronal transcriptomes at …

Neuroscience research has exploded, with more than fifty thousand neuroscientists applying
increasingly advanced methods. A mountain of new facts and mechanisms has emerged …

We describe the development and application of methods for high-throughput
neuroanatomy in Drosophila using light microscopy. These tools enable efficient multicolor …

A growing number of studies have used stylized network models of communication to predict
brain function from structure. Most have focused on a small set of models applied globally …

Animal behaviour arises from computations in neuronal circuits, but our understanding of
these computations has been frustrated by the lack of detailed synaptic connection maps, or …

The anatomy of many neural circuits is being characterized with increasing resolution, but
their molecular properties remain mostly unknown. Here, we characterize gene expression …