Candida parapsilosis: A versatile biocatalyst for organic oxidation-reduction reactions
This review highlights the importance of the biocatalyst, Candida parapsilosis for oxidation
and reduction reactions of organic compounds and establishes its versatility to generate a …
and reduction reactions of organic compounds and establishes its versatility to generate a …
Effective Biotransformation of Ethyl 4-Chloro-3-Oxobutanoate into Ethyl (S)-4-Chloro-3-Hydroxybutanoate by Recombinant E. coli CCZU-T15 Whole Cells in [ChCl] …
Y Dai, B Huan, HS Zhang, YC He - Applied biochemistry and …, 2017 - Springer
To increase the biocatalytic activity of Escherichia coli CCZU-T15 whole cells, choline
chloride/glycerol ([ChCl][Gly]) was firstly used as biocompatible solvent for the effective …
chloride/glycerol ([ChCl][Gly]) was firstly used as biocompatible solvent for the effective …
Engineering of a novel carbonyl reductase with coenzyme regeneration in E. coli for efficient biosynthesis of enantiopure chiral alcohols
P Wei, JX Gao, GW Zheng, H Wu, MH Zong… - Journal of …, 2016 - Elsevier
The novel anti-Prelog stereospecific carbonyl reductase from Acetobacter sp. CCTCC
M209061 was successfully expressed in E. coli combined with glucose dehydrogenase …
M209061 was successfully expressed in E. coli combined with glucose dehydrogenase …
Biosynthesis of optically pure chiral alcohols by a substrate coupled and biphasic system with a short-chain dehydrogenase from Streptomyces griseus
The increasing demand for biocatalysts in synthesizing enantiomerically pure chiral alcohols
results from the outstanding characteristics of enzymes in reaction, economic, ecological …
results from the outstanding characteristics of enzymes in reaction, economic, ecological …
Effective asymmetric bioreduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate by recombinant E. coli CCZU-A13 in [Bmim] PF6 …
It was the first report that the concentrated hydrolyzates from the enzymatic hydrolysis of
dilute NaOH (3 wt%)-soaking rice straw at 30° C was used to form [Bmim] PF 6-hydrolyzate …
dilute NaOH (3 wt%)-soaking rice straw at 30° C was used to form [Bmim] PF 6-hydrolyzate …
Catalytic Synthesis of (S)-CHBE by Directional Coupling and Immobilization of Carbonyl Reductase and Glucose Dehydrogenase
Y Wang, R Sun, P Chen, F Wang - Biomolecules, 2024 - mdpi.com
Ethyl (S)-4-chloro-3-hydroxybutyrate ((S)-CHBE) is an important chiral intermediate in the
synthesis of the cholesterol-lowering drug atorvastatin. Studying the use of …
synthesis of the cholesterol-lowering drug atorvastatin. Studying the use of …
Biocatalytic anti-Prelog reduction of prochiral ketones with whole cells of Acetobacter pasteurianus GIM1.158
PX Du, P Wei, WY Lou, MH Zong - Microbial Cell Factories, 2014 - Springer
Background Enantiomerically pure alcohols are important building blocks for production of
chiral pharmaceuticals, flavors, agrochemicals and functional materials and appropriate …
chiral pharmaceuticals, flavors, agrochemicals and functional materials and appropriate …
Improved biosynthesis of ethyl (S)-4-chloro-3-hydroxybutanoate by adding l-glutamine plus glycine instead of NAD+ in β-cyclodextrin–water system
To reduce dependence on the expensive cofactor and effectively biotransform ethyl 4-chloro-
3-oxobutanoate, l-glutamine and glycine were found to enhance the content of intracellular …
3-oxobutanoate, l-glutamine and glycine were found to enhance the content of intracellular …
Asymmetric synthesis of lipitor chiral intermediate using a robust carbonyl reductase at high substrate to catalyst ratio
GC Xu, MH Tang, Y Ni - Journal of Molecular Catalysis B: Enzymatic, 2016 - Elsevier
An NADPH-dependent carbonyl reductase (RpCR) from Rhodococcus pyridinivorans was
discovered by genome mining for the asymmetric reduction of ethyl 4-chloro-3-oxo …
discovered by genome mining for the asymmetric reduction of ethyl 4-chloro-3-oxo …
Characterization and site-directed mutation of a novel aldo–keto reductase from Lodderomyces elongisporus NRRL YB-4239 with high production rate of ethyl (R)-4 …
Q Wang, T Ye, Z Ma, R Chen, T Xie… - Journal of Industrial …, 2014 - academic.oup.com
A novel aldo–keto reductase (LEK) from Lodderomyces elongisporus NRRL YB-4239
(ATCC 11503) was discovered by genome database mining for carbonyl reduction. LEK was …
(ATCC 11503) was discovered by genome database mining for carbonyl reduction. LEK was …