Recent developments of microfluidics as a tool for biotechnology and microbiology
Highlights•Microfluidics is transforming traditional techniques in biotechnology.•Multi-step
experiments are automated on single device in parallel reactors.•Millions of parallel …
experiments are automated on single device in parallel reactors.•Millions of parallel …
DNA in nanochannels: theory and applications
Nanofluidic structures have over the last two decades emerged as a powerful platform for
detailed analysis of DNA on the kilobase pair length scale. When DNA is confined to a …
detailed analysis of DNA on the kilobase pair length scale. When DNA is confined to a …
Optical DNA mapping in nanofluidic devices: principles and applications
V Müller, F Westerlund - Lab on a Chip, 2017 - pubs.rsc.org
Optical DNA mapping has over the last decade emerged as a very powerful tool for
obtaining long range sequence information from single DNA molecules. In optical DNA …
obtaining long range sequence information from single DNA molecules. In optical DNA …
[HTML][HTML] Molecular Epidemiology of OXA-48 and NDM-1 Producing Enterobacterales Species at a University Hospital in Tehran, Iran, Between 2015 and 2016
H Solgi, S Nematzadeh, CG Giske, F Badmasti… - Frontiers in …, 2020 - frontiersin.org
Carbapenem-resistant Enterobacterales (CRE) is an increasing problem worldwide. Here,
we examined the clonal relatedness of 71 non-repetitive CRE isolates collected in a …
we examined the clonal relatedness of 71 non-repetitive CRE isolates collected in a …
[HTML][HTML] Direct identification of antibiotic resistance genes on single plasmid molecules using CRISPR/Cas9 in combination with optical DNA mapping
Bacterial plasmids are extensively involved in the rapid global spread of antibiotic
resistance. We here present an assay, based on optical DNA mapping of single plasmids in …
resistance. We here present an assay, based on optical DNA mapping of single plasmids in …
Optofluidic systems enabling detection in real samples: A review
Optofluidics, understood as the synergistic combination between microfluidics and
photonics, has been at the forefront of the scientific research due to its outmatching …
photonics, has been at the forefront of the scientific research due to its outmatching …
The HIV-1 nucleocapsid chaperone protein forms locally compacted globules on long double-stranded DNA
The nucleocapsid (NC) protein plays key roles in Human Immunodeficiency Virus 1 (HIV-1)
replication, notably by condensing and protecting the viral RNA genome and by …
replication, notably by condensing and protecting the viral RNA genome and by …
[HTML][HTML] Strain-level bacterial typing directly from patient samples using optical DNA mapping
M Nyblom, A Johnning, K Frykholm, M Wrande… - Communications …, 2023 - nature.com
Background Identification of pathogens is crucial to efficiently treat and prevent bacterial
infections. However, existing diagnostic techniques are slow or have a too low resolution for …
infections. However, existing diagnostic techniques are slow or have a too low resolution for …
Optical DNA mapping combined with Cas9-targeted resistance gene identification for rapid tracking of resistance plasmids in a neonatal intensive care unit outbreak
The global spread of antibiotic resistance among Enterobacteriaceae is largely due to
multidrug resistance plasmids that can transfer between different bacterial strains and …
multidrug resistance plasmids that can transfer between different bacterial strains and …
Optical maps of plasmids as a proxy for clonal spread of MDR bacteria: a case study of an outbreak in a rural Ethiopian hospital
Objectives MDR bacteria have become a prevailing health threat worldwide. We here aimed
to use optical DNA mapping (ODM) as a rapid method to trace nosocomial spread of …
to use optical DNA mapping (ODM) as a rapid method to trace nosocomial spread of …