Hypothalamic AgRP and POMC neurons are conventionally viewed as the yin and yang of
the body's energy status, since they act in an opposite manner to modulate appetite and …

The hypothalamus is an evolutionarily conserved endocrine interface that, among other
roles, links central homeostatic control to adaptive bodily responses by releasing hormones …

Signals from the central circadian pacemaker, the suprachiasmatic nucleus (SCN), must be
decoded to generate daily rhythms in hormone release. Here, we hypothesized that the SCN …

For survival, it is crucial for eating behaviours to be sequenced through two distinct seeking
and consummatory phases. Heterogeneous lateral hypothalamus (LH) neurons are known …

The ability to record transient cellular events in the DNA or RNA of cells would enable
precise, large-scale analysis, selection, and reprogramming of heterogeneous cell …

Neural circuits and the cells that comprise them represent the functional units of the brain.
Circuits relay and process sensory information, maintain homeostasis, drive behaviors, and …

The corticotropin-releasing hormone cells in the paraventricular nucleus of the
hypothalamus (CRHPVN) control the slow endocrine response to stress. The synapses on …

Liraglutide and other glucagon-like peptide 1 receptor agonists (GLP-1RAs) are effective
weight loss drugs, but how they suppress appetite remains unclear. One potential …

BACKGROUND The formation of the nervous system represents an astonishing feat of self-
organization that is compromised in neuropsychiatric conditions such as autism and …

Bisphenol-A (BPA) is an environmental endocrine disruptor and impairs learning and
memory. However, the direct evidence for BPA exposure affecting neural circuits has been …