Matrix Gla Protein (MGP), a small Gla vitamin K-dependent protein, is the most powerful
natural occurring inhibitor of calcification in the human body. To become biologically active …

Patients with chronic kidney disease (CKD) are at increased risk of osteoporosis and
vascular calcification. Bone demineralization and vascular mineralization go often hand in …

Background We investigated the association of vitamin K and vitamin D with coronavirus
disease 2019 (COVID-19) outcomes. Methods Levels of inactive vitamin K–dependent …

Background Arterial calcification is associated with cardiovascular mortality in dialysis
patients. Active matrix Gla protein (MGP) is a vitamin K-dependent inhibitor of arterial …

Arterial calcification is highly prevalent in chronic kidney disease (CKD) patients and is
associated with cardiovascular (CV) morbidity and mortality. Patients at early CKD stages …

Chronic Kidney Disease (CKD) patients are at high risk of presenting with arterial
calcification or stiffness, which confers increased cardiovascular mortality and morbidity. In …

The increase in prevalence and severity of vascular calcification in chronic kidney disease is
a result of complex interactions between changes in the vascular bed, mineral metabolites …

Over the last decades, the association between vascular calcification (VC) and all-
cause/cardiovascular mortality, especially in patients with high atherogenic status, such as …

Although defined by the presence of airflow obstruction and respiratory symptoms, patients
with chronic obstructive pulmonary disease (COPD) are characterized by multimorbidity …

Background Vitamin K activates matrix Gla protein (MGP), a key inhibitor of vascular
calcification. There is a high prevalence of sub-clinical vitamin K deficiency in patients with …