How to resolve microsecond current fluctuations in single ion channels: The power of beta distributions
I Schroeder - Channels, 2015 - Taylor & Francis
A main ingredient for the understanding of structure/function correlates of ion channels is the
quantitative description of single-channel gating and conductance. However, a wealth of …
quantitative description of single-channel gating and conductance. However, a wealth of …
Modulation of BK channels by small endogenous molecules and pharmaceutical channel openers
T Hoshi, SH Heinemann - International review of neurobiology, 2016 - Elsevier
Abstract Voltage-and Ca 2+-activated K+ channels of big conductance (BK channels) are
abundantly found in various organs and their relevance for smooth muscle tone and …
abundantly found in various organs and their relevance for smooth muscle tone and …
Multiscale Responsive Kinetic Modeling: Quantifying Biomolecular Reaction Flux under Varying Electrochemical Conditions
H Weckel-Dahman, R Carlsen… - Journal of Chemical …, 2024 - ACS Publications
Attaining a complete thermodynamic and kinetic characterization for processes involving
multiple interconnected rare-event transitions remains a central challenge in molecular …
multiple interconnected rare-event transitions remains a central challenge in molecular …
Synaptic cleft microenvironment influences potassium permeation and synaptic transmission in hair cells surrounded by calyx afferents in the turtle
D Contini, GR Holstein, JJ Art - The Journal of physiology, 2020 - Wiley Online Library
Key points In central regions of vestibular semicircular canal epithelia, the [K+] in the
synaptic cleft ([K+] c) contributes to setting the hair cell and afferent membrane potentials; …
synaptic cleft ([K+] c) contributes to setting the hair cell and afferent membrane potentials; …
Characterization of the Ca2+-Gated and Voltage-Dependent K+-Channel Slo-1 of Nematodes and Its Interaction with Emodepside
D Kulke, G von Samson-Himmelstjerna… - PLoS neglected …, 2014 - journals.plos.org
The cyclooctadepsipeptide emodepside and its parent compound PF1022A are broad-
spectrum nematicidal drugs which are able to eliminate nematodes resistant to other …
spectrum nematicidal drugs which are able to eliminate nematodes resistant to other …
Novel roles for voltage-gated T-type Ca2+ and ClC-2 channels in phagocytosis and angiogenic factor balance identified in human iPSC-derived RPE.
D Mamaeva, Z Jazouli, ML DiFrancesco… - … : Official Publication of …, 2021 - europepmc.org
Human-induced pluripotent stem cell (hiPSC)-derived retinal pigment epithelium (RPE) is a
powerful tool for pathophysiological studies and preclinical therapeutic screening, as well as …
powerful tool for pathophysiological studies and preclinical therapeutic screening, as well as …
Ca2+ block and flickering both contribute to the negative slope of the IV curve in BK channels
I Schroeder, G Thiel, UP Hansen - Journal of General Physiology, 2013 - rupress.org
Single-channel current–voltage (IV) curves of human large-conductance, voltage-and Ca2+-
activated K+ (BK) channels are quite linear in 150 mM KCl. In the presence of Ca2+ and/or …
activated K+ (BK) channels are quite linear in 150 mM KCl. In the presence of Ca2+ and/or …
17 BK channels
H Yang, J Cui - api.taylorfrancis.com
Large conductance, voltage, and Ca2+-activated K+ channels are known as BK or MaxiK
channels to denote the large single channel conductance of 100–300 pS (Figure 17.1). BK …
channels to denote the large single channel conductance of 100–300 pS (Figure 17.1). BK …
[PDF][PDF] Characterisation of the calcium-gated and voltage-dependent potassium channel SLO-1 of nematodes and its interaction with emodepside
D Kulde, G von Samson-Himmelstcerna… - Analysis of the efficacy … - refubium.fu-berlin.de
The cyclooctadeisiieitide emodeiside and its iarental comiound PF1022A are very [road
siectrum nematicidal drugs which are a [le to eliminate nematodes resistant to other …
siectrum nematicidal drugs which are a [le to eliminate nematodes resistant to other …