Mesenchymal stem cell-derived exosomes and other extracellular vesicles as new remedies in the therapy of inflammatory diseases
CR Harrell, N Jovicic, V Djonov, N Arsenijevic… - Cells, 2019 - mdpi.com
There is growing evidence that mesenchymal stem cell (MSC)-based immunosuppression
was mainly attributed to the effects of MSC-derived extracellular vesicles (MSC-EVs). MSC …
was mainly attributed to the effects of MSC-derived extracellular vesicles (MSC-EVs). MSC …
[HTML][HTML] Ethical and safety issues of stem cell-based therapy
V Volarevic, BS Markovic, M Gazdic… - … journal of medical …, 2018 - ncbi.nlm.nih.gov
Results obtained from completed and on-going clinical studies indicate huge therapeutic
potential of stem cell-based therapy in the treatment of degenerative, autoimmune and …
potential of stem cell-based therapy in the treatment of degenerative, autoimmune and …
The immunomodulatory functions of mesenchymal stromal/stem cells mediated via paracrine activity
Y Zhou, Y Yamamoto, Z Xiao, T Ochiya - Journal of clinical medicine, 2019 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) exist in almost all tissues, possessing the potential
to differentiate into specialized cell types and exert immunomodulatory functions. Thus, they …
to differentiate into specialized cell types and exert immunomodulatory functions. Thus, they …
Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
Emerging treatments for inflammatory bowel disease
K Hazel, A O'Connor - Therapeutic advances in chronic …, 2020 - journals.sagepub.com
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), is characterized by chronic inflammation, a relapsing and remitting clinical course …
(UC), is characterized by chronic inflammation, a relapsing and remitting clinical course …
The therapeutic potential of stem cell-derived exosomes in the ulcerative colitis and colorectal cancer
G Guo, Z Tan, Y Liu, F Shi, J She - Stem cell research & therapy, 2022 - Springer
Abstract Background Mesenchymal stem cells (MSCs) therapy is a novel treatment strategy
for cancer and a wide range of diseases with an excessive immune response such as …
for cancer and a wide range of diseases with an excessive immune response such as …
Autologous mesenchymal stem cells improve motor recovery in subacute ischemic stroke: a randomized clinical trial
A Jaillard, M Hommel, A Moisan, TA Zeffiro… - Translational stroke …, 2020 - Springer
While preclinical stroke studies have shown that mesenchymal stem cells (MSCs) promote
recovery, few randomized controlled trials (RCT) have assessed cell therapy in humans. In …
recovery, few randomized controlled trials (RCT) have assessed cell therapy in humans. In …
An update on the progress of isolation, culture, storage, and clinical application of human bone marrow mesenchymal stem/stromal cells
DT Chu, TNT Phuong, NLB Tien, DK Tran… - International journal of …, 2020 - mdpi.com
Bone marrow mesenchymal stem/stromal cells (BMSCs), which are known as multipotent
cells, are widely used in the treatment of various diseases via their self-renewable …
cells, are widely used in the treatment of various diseases via their self-renewable …
Shining the light on clinical application of mesenchymal stem cell therapy in autoimmune diseases
SA Jasim, AV Yumashev, WK Abdelbasset… - Stem Cell Research & …, 2022 - Springer
The autoimmune diseases are associated with the host immune system, chronic
inflammation, and immune reaction against self-antigens, which leads to the injury and …
inflammation, and immune reaction against self-antigens, which leads to the injury and …
Potency analysis of mesenchymal stromal cells using a combinatorial assay matrix approach
R Chinnadurai, D Rajan, M Qayed, D Arafat, M Garcia… - Cell reports, 2018 - cell.com
Assays that can characterize MSC immune potency need to be identified for use in
advanced clinical trials. MSCs possess a number of putative regenerative and …
advanced clinical trials. MSCs possess a number of putative regenerative and …