Etiology and pathogenesis of preeclampsia: current concepts
GA Dekker, BM Sibai - American journal of obstetrics and gynecology, 1998 - Elsevier
The etiology of preeclampsia is unknown. At present, 4 hypotheses are the subject of
extensive investigation, as follows:(1) Placental ischemia—Increased trophoblast …
extensive investigation, as follows:(1) Placental ischemia—Increased trophoblast …
Nitric oxide and pregnancy
SM Sladek, RR Magness… - American Journal of …, 1997 - journals.physiology.org
This review will consider whether nitric oxide (NO) contributes to maternal systemic
vasodilation during pregnancy, regulates uterine and fetoplacental blood flow, and is …
vasodilation during pregnancy, regulates uterine and fetoplacental blood flow, and is …
[图书][B] The pathology of the human placenta
K Benirschke, SG Driscoll - 1967 - Springer
This presentation of the diseases of the placenta differs in many ways from the first such
treatment in these volumes by the eminent Robert Meyer. It is a deliberate attempt to bring …
treatment in these volumes by the eminent Robert Meyer. It is a deliberate attempt to bring …
Hormonal regulation of nitric oxide synthases and their cell-specific expression during follicular development in the rat ovary
A Jablonka-Shariff, LM Olson - Endocrinology, 1997 - academic.oup.com
Nitric oxide (NO) has emerged as a novel regulator of several ovarian events, such as
ovulation, steroidogenesis, and apoptotic cell death. The NO synthases (NOS) are a family …
ovulation, steroidogenesis, and apoptotic cell death. The NO synthases (NOS) are a family …
Heme oxygenase expression in human placenta and placental bed: reduced expression of placenta endothelial HO‐2 in preeclampsia and fetal growth restriction
A Barber, SC Robson, L Myatt, JN Bulmer… - The FASEB …, 2001 - Wiley Online Library
In this study we tested the hypothesis that expression of heme oxygenases HO‐1 and HO‐2,
which are responsible for the production of carbon monoxide, are reduced in the placenta …
which are responsible for the production of carbon monoxide, are reduced in the placenta …
Cigarette smoking and pregnancy II: vascular effects
C Salafia, K Shiverick - Placenta, 1999 - Elsevier
The act of smoking introduces a complex set of chemicals that have a broad range of effects,
both complementary and antagonistic, at various levels within the vascular tree. A general …
both complementary and antagonistic, at various levels within the vascular tree. A general …
Evaluation of nitric oxide as a mediator of severe preeclampsia
RK Silver, MJ Kupferminc, TL Russell, L Adler… - American journal of …, 1996 - Elsevier
OBJECTIVE: Our purpose was to determine whether a reduction in nitric oxide synthesis
occurs in women with severe preeclampsia as a consequence of soluble serum factors …
occurs in women with severe preeclampsia as a consequence of soluble serum factors …
Expression and relationship between endothelin-1 messenger ribonucleic acid (mRNA) and inducible/endothelial nitric oxide synthase mRNA isoforms from normal …
M Napolitano, F Miceli, A Calce, A Vacca… - The Journal of …, 2000 - academic.oup.com
Preeclampsia is a mainly vascular disease of pregnancy, probably caused by an imbalance
between vasodilator and vasoconstrictor agents that results in generalized vasospasm and …
between vasodilator and vasoconstrictor agents that results in generalized vasospasm and …
Nitric oxide concentrations are increased in the feto-placental circulation in intrauterine growth restriction
F Lyall, IA Greer, A Young, L Myatt - Placenta, 1996 - Elsevier
The aim of this study was to measure plasma concentrations of total nitrites, as an index of
nitric oxide (NO) synthesis, in the fetal circulation of normal pregnancies and in pregnancies …
nitric oxide (NO) synthesis, in the fetal circulation of normal pregnancies and in pregnancies …
Phenotype of the endothelium in the human term placenta
JF Dye, R Jablenska, JL Donnelly, L Lawrence… - Placenta, 2001 - Elsevier
The placental endothelium contributes to regulating transplacental exchange and
maintaining the immunological maternofetal barrier. We characterized the endothelial …
maintaining the immunological maternofetal barrier. We characterized the endothelial …