Fourth universal definition of myocardial infarction (2018)

K Thygesen, JS Alpert, AS Jaffe, BR Chaitman, JJ Bax… - Circulation, 2018 - Am Heart Assoc
In the late 19th century, postmortem examinations demonstrated a possible relationship
between thrombotic occlusion of a coronary artery and myocardial infarction (MI). 1 …

Cardiac troponin assays: guide to understanding analytical characteristics and their impact on clinical care

FS Apple, Y Sandoval, AS Jaffe… - Clinical …, 2017 - academic.oup.com
Abstract BACKGROUND Cardiac troponin I (cTnI) and cardiac troponin T (cTnT)
determinations are fixtures in clinical practice and research. Cardiac troponin testing has …

2022 ACC expert consensus decision pathway on the evaluation and disposition of acute chest pain in the emergency department: a report of the American College of …

Writing Committee, MC Kontos, JA de Lemos… - Journal of the American …, 2022 - jacc.org
Copies: This document is available on the website of the American College of Cardiology
(www. acc. org). For copies of this document, please contact Elsevier Inc. Reprint …

High-sensitivity cardiac troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR guidelines for the evaluation and diagnosis of acute chest pain

Y Sandoval, FS Apple, SA Mahler, R Body… - Circulation, 2022 - Am Heart Assoc
The 2021 American Heart Association/American College of Cardiology/American Society of
Echocardiography/American College of Chest Physicians/Society for Academic Emergency …

Cardiac troponins: contemporary biological data and new methods of determination

A Chaulin - Vascular health and risk management, 2021 - Taylor & Francis
Laboratory diagnosis plays one of the key roles in the diagnosis of many diseases, including
cardiovascular diseases (CVD). The methods underlying the in vitro study of many CVD …

Clinical validation of a novel high-sensitivity cardiac troponin I assay for early diagnosis of acute myocardial infarction

J Boeddinghaus, R Twerenbold… - Clinical …, 2018 - academic.oup.com
BACKGROUND Clinical performance of the novel high-sensitivity cardiac troponin I
(Siemens-hs-cTnI-Centaur) assay is unknown. We aimed to clinically validate the Siemens …

Ultrasensitive chemiluminescence immunoassay with enhanced precision for the detection of cTnI amplified by acridinium ester-loaded microspheres and internally …

H Zhao, Q Lin, L Huang, Y Zhai, Y Liu, Y Deng, E Su… - Nanoscale, 2021 - pubs.rsc.org
A novel enhanced chemiluminescent immunoassay (CLIA) for ultrasensitive and excellent
precisive determination of cardiac troponin I (cTnI) was reported. The method made full use …

Sex-specific 99th percentile upper reference limits for high sensitivity cardiac troponin assays derived using a universal sample bank

FS Apple, AHB Wu, Y Sandoval, A Sexter… - Clinical …, 2020 - academic.oup.com
Background How to select healthy reference subjects in deriving 99th percentiles for cardiac
troponin assays still needs to be clarified. To assist with global implementation of high …

Single high-sensitivity point-of-care whole-blood cardiac troponin I measurement to rule out acute myocardial infarction at low risk

FS Apple, SW Smith, JH Greenslade, Y Sandoval… - Circulation, 2022 - Am Heart Assoc
Background: High-sensitivity cardiac troponin (hs-cTn) laboratory assays are used to rule
out myocardial infarction (MI) on presentation, but prolonged result turnaround times can …

Washing-free chemiluminescence immunoassay for rapid detection of cardiac troponin I in whole blood samples

H Zhao, E Su, L Huang, Y Zai, Y Liu, Z Chen, S Li… - Chinese Chemical …, 2022 - Elsevier
Chemiluminescence immunoassay (CLIA) has always been a great challenge in detecting
cardiac troponin I (cTnI) in whole blood samples without centrifugation because of the …