[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …
treatment strategies, it remains a prominent cause of female mortality worldwide …
Challenges and recent progress in oral drug delivery systems for biopharmaceuticals
B Homayun, X Lin, HJ Choi - Pharmaceutics, 2019 - mdpi.com
Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …
given route play significant roles in therapeutic efficacy and short term/long term biological …
Cell adhesion molecules and their roles and regulation in the immune and tumor microenvironment
H Harjunpää, M Llort Asens, C Guenther… - Frontiers in …, 2019 - frontiersin.org
The immune system and cancer have a complex relationship with the immune system
playing a dual role in tumor development. The effector cells of the immune system can …
playing a dual role in tumor development. The effector cells of the immune system can …
MUC1: structure, function, and clinic application in epithelial cancers
W Chen, Z Zhang, S Zhang, P Zhu, JKS Ko… - International journal of …, 2021 - mdpi.com
The transmembrane glycoprotein mucin 1 (MUC1) is a mucin family member that has
different functions in normal and cancer cells. Owing to its structural and biochemical …
different functions in normal and cancer cells. Owing to its structural and biochemical …
Biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values
Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …
organisms at the molecular to the whole-body level, inducing the so-called state of stress …
Ligand-targeted drug delivery
M Srinivasarao, PS Low - Chemical reviews, 2017 - ACS Publications
Safety and efficacy constitute the major criteria governing regulatory approval of any new
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …
The impact of the endoplasmic reticulum protein-folding environment on cancer development
M Wang, RJ Kaufman - Nature Reviews Cancer, 2014 - nature.com
The endoplasmic reticulum (ER) is an essential organelle in eukaryotic cells for the storage
and regulated release of calcium and as the entrance to the secretory pathway. Protein …
and regulated release of calcium and as the entrance to the secretory pathway. Protein …
Mucinous colorectal adenocarcinoma: clinical pathology and treatment options
C Luo, S Cen, G Ding, W Wu - Cancer communications, 2019 - Springer
Mucinous colorectal adenocarcinoma is a distinct subtype of colorectal cancer (CRC)
characterized by the presence of abundant extracellular mucin which accounts for at least …
characterized by the presence of abundant extracellular mucin which accounts for at least …
Inter-tissue communication in cancer cachexia
JM Argilés, B Stemmler, FJ López-Soriano… - Nature Reviews …, 2019 - nature.com
Cachexia is a systemic condition that occurs during many neoplastic diseases, such as
cancer. Cachexia in cancer is characterized by loss of body weight and muscle and by …
cancer. Cachexia in cancer is characterized by loss of body weight and muscle and by …
The emerging role of the mammalian glycocalyx in functional membrane organization and immune system regulation
L Möckl - Frontiers in cell and developmental biology, 2020 - frontiersin.org
All cells in the human body are covered by a dense layer of sugars and the proteins and
lipids to which they are attached, collectively termed the “glycocalyx.” For decades, the …
lipids to which they are attached, collectively termed the “glycocalyx.” For decades, the …