Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …

The immune system and cancer have a complex relationship with the immune system
playing a dual role in tumor development. The effector cells of the immune system can …

The transmembrane glycoprotein mucin 1 (MUC1) is a mucin family member that has
different functions in normal and cancer cells. Owing to its structural and biochemical …

Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

Safety and efficacy constitute the major criteria governing regulatory approval of any new
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …

The endoplasmic reticulum (ER) is an essential organelle in eukaryotic cells for the storage
and regulated release of calcium and as the entrance to the secretory pathway. Protein …

Mucinous colorectal adenocarcinoma is a distinct subtype of colorectal cancer (CRC)
characterized by the presence of abundant extracellular mucin which accounts for at least …

Cachexia is a systemic condition that occurs during many neoplastic diseases, such as
cancer. Cachexia in cancer is characterized by loss of body weight and muscle and by …

All cells in the human body are covered by a dense layer of sugars and the proteins and
lipids to which they are attached, collectively termed the “glycocalyx.” For decades, the …