CRISPR/Cas9 genome editing has gained rapidly increasing attentions in recent years,
however, the translation of this biotechnology into therapy has been hindered by efficient …

Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …

The non-conventional oleaginous yeast Yarrowia lipolytica shows great industrial promise. It
naturally produces certain compounds of interest but can also artificially generate non-native …

Highlights•The yeasts, Cutaneotrichosporon oleaginosus, Lipomyces starkeyi, and
Rhodosporidium toruloides, grow on a wide range of substrates and naturally outperform …

Unusual fatty acids with special carbon chain length or functional groups have been
extensively used in the chemical, material, nutraceutical, and pharmaceutical industries. The …

Filamentous fungi are critical in the transition to a more sustainable food system. While
genetic modification of these organisms has promise for enhancing the nutritional value …

Yarrowia lipolytica is characterized by GRAS (Generally regarded as safe) status, the
versatile substrate utilization profile, rapid utilization rates, metabolic diversity and flexibility …

Geraniol is a monoterpene with wide applications in the food, cosmetics, and
pharmaceutical industries. Microbial production has largely used model organisms lacking …

Owing to the important physiological functions, polyunsaturated fatty acids (PUFAs) play a
vital role in protecting human health, such as preventing cancer, cardiovascular disease …

Yarrowia lipolytica has been extensively used to produce essential chemicals and enzymes.
As in most other eukaryotes, nonhomologous end joining (NHEJ) is the major repair …