[HTML][HTML] GLP-1 receptor agonists: beyond their pancreatic effects

X Zhao, M Wang, Z Wen, Z Lu, L Cui, C Fu… - Frontiers in …, 2021 - frontiersin.org
Glucagon like peptide-1 (GLP-1) is an incretin secretory molecule. GLP-1 receptor agonists
(GLP-1RAs) are widely used in the treatment of type 2 diabetes (T2DM) due to their …

The anti-inflammatory and immunological properties of GLP-1 Receptor Agonists

G Bendotti, L Montefusco, ME Lunati, V Usuelli… - Pharmacological …, 2022 - Elsevier
In the last few years, a great interest has emerged in investigating the pleiotropic effects of
Glucagon Like Peptide-1 Receptor Agonists (GLP-1RAs). While GLP-1RAs ability to lower …

[HTML][HTML] GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential

X Ma, Z Liu, I Ilyas, PJ Little, D Kamato… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Type 2 diabetes mellitus (T2DM) is closely associated with cardiovascular diseases (CVD),
including atherosclerosis, hypertension and heart failure. Some anti-diabetic medications …

Macrophage polarization in atherosclerosis

S Yang, HQ Yuan, YM Hao, Z Ren, SL Qu, LS Liu… - Clinica Chimica …, 2020 - Elsevier
Atherosclerosis is a chronic inflammatory response that increases the risk of cardiovascular
diseases. An in-depth study of the pathogenesis of atherosclerosis is critical for the treatment …

Time-dependent effect of GLP-1 receptor agonists on cardiovascular benefits: a real-world study

S Piccini, G Favacchio, C Panico, E Morenghi… - Cardiovascular …, 2023 - Springer
Background Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have shown
cardiovascular benefits in cardiovascular outcome trials in type 2 diabetes mellitus …

Endothelial dysfunction in diabetes

Y Takeda, K Matoba, K Sekiguchi, Y Nagai, T Yokota… - Biomedicines, 2020 - mdpi.com
Diabetes is a worldwide health issue closely associated with cardiovascular events. Given
the pandemic of obesity, the identification of the basic underpinnings of vascular disease is …

Adipose tissue as a key player in obstructive sleep apnoea

S Ryan, C Arnaud, SF Fitzpatrick… - European …, 2019 - Eur Respiratory Soc
Obstructive sleep apnoea (OSA) is a major health concern worldwide and adversely affects
multiple organs and systems. OSA is associated with obesity in> 60% of cases and is …

Effect of liraglutide on cardiac function in patients with type 2 diabetes mellitus: randomized placebo-controlled trial

MB Bizino, IM Jazet, JJM Westenberg… - Cardiovascular …, 2019 - Springer
Background Liraglutide is an antidiabetic agent with cardioprotective effect. The purpose of
this study is to test efficacy of liraglutide to improve diabetic cardiomyopathy in patients with …

Comparison of effects of SGLT-2 inhibitors and GLP-1 receptor agonists on cardiovascular and renal outcomes in type 2 diabetes mellitus patients with/without …

Y Kawai, K Uneda, T Yamada, S Kinguchi… - Diabetes Research and …, 2022 - Elsevier
Aims It remains unclear which sodium-glucose cotransporter-2 (SGLT-2) inhibitors and
glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are most effective for preventing …

Cardiorenal protection: potential of SGLT2 inhibitors and GLP-1 receptor agonists in the treatment of type 2 diabetes

T Nagahisa, Y Saisho - Diabetes Therapy, 2019 - Springer
Recent large clinical trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors and
glucagon-like peptide-1 (GLP-1) receptor agonists, with the aim of verifying cardiovascular …