[HTML][HTML] Tracing genetic diversity captures the molecular basis of misfolding disease

P Zhao, C Wang, S Sun, X Wang, WE Balch - Nature Communications, 2024 - nature.com
Genetic variation in human populations can result in the misfolding and aggregation of
proteins, giving rise to systemic and neurodegenerative diseases that require management …

[HTML][HTML] COPII cage assembly factor Sec13 integrates information flow regulating endomembrane function in response to human variation

F Anglès, V Gupta, C Wang, WE Balch - Scientific Reports, 2024 - nature.com
How information flow is coordinated for managing transit of 1/3 of the genome through
endomembrane pathways by the co at com p lex II (COPII) system in response to human …