Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches
IA Savin, MA Zenkova, AV Sen'kova - International journal of molecular …, 2022 - mdpi.com
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …
Osteopontin takes center stage in chronic liver disease
Osteopontin (OPN) was first identified in 1986. The prefix osteo‐means bone; however, OPN
is expressed in other tissues, including liver. The suffix‐pontin means bridge and denotes …
is expressed in other tissues, including liver. The suffix‐pontin means bridge and denotes …
A synthetic metastatic niche reveals antitumor neutrophils drive breast cancer metastatic dormancy in the lungs
Biomaterial scaffolds mimicking the environment in metastatic organs can deconstruct
complex signals and facilitate the study of cancer progression and metastasis. Here we …
complex signals and facilitate the study of cancer progression and metastasis. Here we …
Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes
Axon regeneration holds great promise for neural repair of CNS axonopathies, including
glaucoma. Pten deletion in retinal ganglion cells (RGCs) promotes potent optic nerve …
glaucoma. Pten deletion in retinal ganglion cells (RGCs) promotes potent optic nerve …
The significance of SPP1 in lung cancers and its impact as a marker for protumor tumor-associated macrophages
E Matsubara, H Yano, C Pan, Y Komohara, Y Fujiwara… - Cancers, 2023 - mdpi.com
Simple Summary Macrophages that infiltrate the cancer microenvironment are referred to as
tumor-associated macrophages (TAMs). Phosphoprotein 1 (SPP1), also known as …
tumor-associated macrophages (TAMs). Phosphoprotein 1 (SPP1), also known as …
Osteopontin in cardiovascular diseases
K Shirakawa, M Sano - Biomolecules, 2021 - mdpi.com
Unprecedented advances in secondary prevention have greatly improved the prognosis of
cardiovascular diseases (CVDs); however, CVDs remain a leading cause of death globally …
cardiovascular diseases (CVDs); however, CVDs remain a leading cause of death globally …
T cell immunosenescence in aging, obesity, and cardiovascular disease
K Shirakawa, M Sano - Cells, 2021 - mdpi.com
Although advances in preventive medicine have greatly improved prognosis, cardiovascular
disease (CVD) remains the leading cause of death worldwide. This clearly indicates that …
disease (CVD) remains the leading cause of death worldwide. This clearly indicates that …
[HTML][HTML] An all-silk-derived bilayer hydrogel for osteochondral tissue engineering
W Jiang, X Xiang, M Song, J Shen, Z Shi, W Huang… - Materials Today Bio, 2022 - Elsevier
Osteochondral repair remains a challenge in clinical practice nowadays despite extensive
advances in tissue engineering. The insufficient recruitment of endogenous cells in the early …
advances in tissue engineering. The insufficient recruitment of endogenous cells in the early …
Progress and prospects of biomarkers in primary liver cancer
YX Gao, TW Yang, JM Yin… - International …, 2020 - spandidos-publications.com
Tumor biomarkers are important in the early screening, diagnosis, therapeutic evaluation,
recurrence and prognosis prediction of tumors. Primary liver cancer is one of the most …
recurrence and prognosis prediction of tumors. Primary liver cancer is one of the most …
Examining the function of macrophage oxidative stress response and immune system in glioblastoma multiforme through analysis of single-cell transcriptomics
J Xing, H Cai, Z Lin, L Zhao, H Xu, Y Song… - Frontiers in …, 2024 - frontiersin.org
Background Glioblastoma (GBM), a prevalent malignant neoplasm within the neuro-
oncological domain, has been a subject of considerable scrutiny. Macrophages, serving as …
oncological domain, has been a subject of considerable scrutiny. Macrophages, serving as …