T-type Ca2+ channels were originally called low-voltage-activated (LVA) channels because
they can be activated by small depolarizations of the plasma membrane. In many neurons …

Calcium regulates a wide spectrum of physiological processes such as heartbeat, muscle
contraction, neuronal communication, hormone release, cell division, and gene …

Elevated intracellular Ca 2+ triggers inactivation of L-type calcium channels, providing
negative Ca 2+ feedback in many cells. Ca 2+ binding to the main α 1C channel subunit has …

N-type voltage-gated calcium (Ca V) channels mediate Ca 2+ influx at presynaptic terminals
in response to action potentials and play vital roles in synaptogenesis, release of …

Short-term depression is a widespread form of use-dependent plasticity found in the
peripheral and central nervous systems of invertebrates and vertebrates. The mechanism …

Acute modulation of P/Q-type (α1A) calcium channels by neuronal activity-dependent
changes in intracellular Ca2+ concentration may contribute to short-term synaptic plasticity …

We have examined factors that determine the strength and dynamics of GABAergic
synapses between interneurons [dentate gyrus basket cells (BCs)] and principal neurons …

The somatodendritic subthreshold A-type K+ current (ISA) in nerve cells is a critical
component of the ensemble of voltage-gated ionic currents that determine somatodendritic …

Abstract L-type (Ca V 1.2) and P/Q-type (Ca V 2.1) calcium channels possess lobe-specific
CaM regulation, where Ca 2+ binding to one or the other lobe of CaM triggers regulation …

Short term plasticity is a highly abundant form of rapid, activity-dependent modulation of
synaptic efficacy. A shared set of mechanisms can cause both depression and enhancement …