Revisiting 'progressive stroke': incidence, predictors, pathophysiology, and management of unexplained early neurological deterioration following acute ischemic …

P Seners, JC Baron - Journal of neurology, 2018 - Springer
Early neurological deterioration (END) following acute ischemic stroke is a serious clinical
event strongly associated with poor outcome. Regarding specifically END occurring within …

Prediction of early neurological deterioration in individuals with minor stroke and large vessel occlusion intended for intravenous thrombolysis alone

P Seners, WB Hassen, B Lapergue, C Arquizan… - JAMA …, 2021 - jamanetwork.com
Importance The best reperfusion strategy in patients with acute minor stroke and large
vessel occlusion (LVO) is unknown. Accurately predicting early neurological deterioration of …

The core/penumbra model: implications for acute stroke treatment and patient selection in 2021

JC Baron - European Journal of Neurology, 2021 - Wiley Online Library
Despite major advances in prevention, ischaemic stroke remains one of the leading causes
of death and disability worldwide. After centuries of nihilism and decades of failed …

Predictors of unexplained early neurological deterioration after endovascular treatment for acute ischemic stroke

JB Girot, S Richard, F Gariel, I Sibon, J Labreuche… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: Although the efficacy of endovascular treatment (EVT) in patients
with anterior circulation ischemic stroke (AIS) is well documented, early neurological …

Minor stroke due to large artery occlusion. When is intravenous thrombolysis not enough? Results from the SITS International Stroke Thrombolysis Register

MV Mazya, C Cooray, KR Lees, D Toni… - European stroke …, 2018 - journals.sagepub.com
Purpose Beyond intravenous thrombolysis, evidence is lacking on acute treatment of minor
stroke caused by large artery occlusion. To identify candidates for additional endovascular …

The incidence and associated factors of early neurological deterioration after thrombolysis: results from SITS registry

WM Yu, AH Abdul-Rahim, AC Cameron, J Kõrv… - Stroke, 2020 - Am Heart Assoc
Background and purpose: Early neurological deterioration (END) after stroke onset may
predict severe outcomes. Estimated rates of END after intravenous thrombolysis among …

Early neurological deterioration after thrombolysis: clinical and imaging predictors

CZ Simonsen, ML Schmitz… - … Journal of Stroke, 2016 - journals.sagepub.com
Background National Institutes of Health Stroke Scale is the most common scale used in
stroke patients. An increase of four points or more within 24 h signifies early neurological …

Prediction of early neurological deterioration in acute ischemic stroke patients treated with intravenous thrombolysis

T Tian, L Wang, J Xu, Y Jia, K Xue… - Journal of Cerebral …, 2023 - journals.sagepub.com
A proportion of acute ischemic stroke (AIS) patients suffer from early neurological
deterioration (END) within 24 hours following intravenous thrombolysis (IVT), which greatly …

Minor stroke syndromes in large-vessel occlusions: mechanical thrombectomy or thrombolysis only?

MP Messer, S Schönenberger… - American Journal …, 2017 - Am Soc Neuroradiology
While mechanical thrombectomy for large-vessel occlusions is now an evidence-based
treatment, its efficacy and safety in minor stroke syndromes (NIHSS≤ 5) is not proved. We …

Is unexplained early neurological deterioration after intravenous thrombolysis associated with thrombus extension?

P Seners, R Hurford, M Tisserand, G Turc, L Legrand… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Early neurological deterioration (END) after anterior circulation
stroke is strongly associated with poor outcome. Apart from straightforward causes, such as …