Accumulating data support the importance of interactions between pre-and postsynaptic
neuronal elements with astroglial processes and extracellular matrix (ECM) for formation …

The emergence of astroglia as an important participant of the synaptic machinery has led to
the 'tripartite synapse'hypothesis. Recent findings suggest that synaptic signaling also …

The major glial population of the brain is constituted by astroglia. Highly branched and
ramified protoplasmic astrocytes are the predominant form in grey matter and are found in …

The extracellular matrix (ECM) of the central nervous system is well recognized as a
migration and diffusion barrier that allows for the trapping and presentation of growth factors …

During postnatal development, changes in the subunit composition of glutamate receptors of
the NMDA subtype (NMDARs) are key to the refinement of excitatory synapses. Hypotheses …

Perineuronal nets (PNNs) were shown to be markedly altered in subjects with
schizophrenia. In particular, decreases of PNNs have been detected in the amygdala …

In the adult brain, synapses are tightly enwrapped by lattices of the extracellular matrix that
consist of extremely long-lived molecules. These lattices are deemed to stabilize synapses …

The extracellular matrix (ECM) of the brain has important roles in regulating synaptic
function and plasticity. A juvenile ECM supports the wiring of neuronal networks …

In higher vertebrates, the extracellular matrix (ECM) wrapping cells of the adult brain differs
significantly from that of the developing and juvenile brain. The mature ECM is established …

Chondroitin sulfate (CS) is the most abundant and widely distributed glycosaminoglycan
(GAG) in the human body. As a component of proteoglycans (PGs) it has numerous roles in …