Importance of paraoxonase 1 (PON1) as an antioxidant and antiatherogenic enzyme in the cardiovascular complications of type 2 diabetes: Genotypic and phenotypic …

Y Shokri, A Variji, M Nosrati, A Khonakdar-Tarsi… - Diabetes research and …, 2020 - Elsevier
Oxidant–antioxidant imbalance is involved in the etiology of different diseases, including
cardiovascular diseases (CVDs), liver disorders, kidney diseases, cancers and diabetes …

[HTML][HTML] Early biomarkers of neurodegenerative and neurovascular disorders in diabetes

A Gasecka, D Siwik, M Gajewska… - Journal of Clinical …, 2020 - mdpi.com
Diabetes mellitus (DM) is a common disease worldwide. There is a strong association
between DM and neurovascular and neurodegenerative disorders. The first group mainly …

The role of paraoxonase in cancer

T Bacchetti, G Ferretti, A Sahebkar - Seminars in câncer biology, 2019 - Elsevier
The paraoxonase (PON) gene family includes three proteins, PON1, PON2 and PON3.
PON1 and PON3 are both associated with high-density lipoprotein (HDL) particles and exert …

The role of high-density lipoprotein cholesterol, apolipoprotein A and paraoxonase-1 in the pathophysiology of neuroprogressive disorders

G Morris, BK Puri, CC Bortolasci, A Carvalho… - Neuroscience & …, 2021 - Elsevier
Lowered high-density lipoprotein (HDL) cholesterol has been reported in major depressive
disorder, bipolar disorder, first episode of psychosis, and schizophrenia. HDL, its major …

Functional foods and nutraceuticals as therapeutic tools for the treatment of diet-related diseases

T Magrone, F Perez de Heredia, E Jirillo… - Canadian journal of …, 2013 - cdnsciencepub.com
In Western societies, the incidence of diet-related diseases is progressively increasing due
to greater availability of hypercaloric food and a sedentary lifestyle. Obesity, diabetes …

Why should psychiatrists and neuroscientists worry about paraoxonase 1?

EG Moreira, KM Boll, DG Correia… - Current …, 2019 - ingentaconnect.com
Background: Nitro-oxidative stress (NOS) has been implicated in the pathophysiology of
psychiatric disorders. The activity of the polymorphic antioxidant enzyme paraoxonase 1 …

Lycopene improves the metformin effects on glycemic control and decreases biomarkers of glycoxidative stress in diabetic rats

ID Figueiredo, TFO Lima, MD Inácio… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Introduction Oxidative stress and exacerbated generation of advanced glycation end
products (AGEs) participate in the onset of diabetic complications. Lycopene is a potent …

[HTML][HTML] Posicionamiento en torno al diagnóstico y tratamiento de las dislipidemias

AD Aragón, CLF Barros, JME Muñoz… - Revista Mexicana de …, 2018 - medigraphic.com
La prevención y el tratamiento de todas las formas de dislipidemia son tareas
fundamentales que evitan o retrasan el desarrollo de la aterosclerosis y de otras …

Soluble lectin‐like oxidized LDL receptor 1 as a possible mediator of endothelial dysfunction in patients with metabolic syndrome

S Civelek, M Kutnu, H Uzun, F Erdenen… - Journal of Clinical …, 2015 - Wiley Online Library
Background Metabolic syndrome (MetS) defines a well‐known cluster of metabolic
disturbances associated with an increased risk of cardiovascular disease and diabetes. The …

The paraoxonase 1 (PON1), platelet-activating factor acetylohydrolase (PAF-AH) and dimethylarginine dimethylaminohydrolase (DDAH) activity in the metformin …

G Wójcicka, A Jamroz-Wiśniewska… - European journal of …, 2016 - Elsevier
Antidiabetic agents per se, apart from their glucose-lowering effect, can have an important
impact on modifying the cardiovascular risk. The present study was undertaken to determine …