Importance Eosinophilic esophagitis (EoE) is a chronic immune-mediated inflammatory
disease of the esophagus that affects an estimated 34.4/100 000 people in Europe and …

Background There is currently no recommendation regarding preferred drugs for active
eosinophilic oesophagitis (EoE) because their relative efficacy is unclear. We conducted an …

Background Benralizumab is an eosinophil-depleting anti–interleukin-5 receptor α
monoclonal antibody. The efficacy and safety of benralizumab in patients with eosinophilic …

Background Eosinophilic oesophagitis (EoE) is an increasingly common cause of dysphagia
in both children and adults, as well as one of the most prevalent oesophageal diseases with …

Objective We aimed to determine whether mepolizumab, an anti-IL-5 antibody, was more
effective than placebo for improving dysphagia symptoms and decreasing oesophageal …

Background & Aims There are no studies or recommendations on optimal monitoring
strategies for patients with eosinophilic esophagitis (EoE). Our objective was to develop …

Background End points used to determine treatment efficacy in eosinophilic esophagitis
(EoE) have evolved over time. With multiple novel therapies in development for EoE …

Eosinophilic esophagitis (EoE) is an increasingly common inflammatory allergic disease of
the esophagus characterized by esophageal eosinophilia and symptoms of esophageal …

Background & Aims Eosinophilic esophagitis (EoE) can progress to fibrostenosis by unclear
mechanisms. Herein, we investigated gene dysregulation in fibrostenotic EoE, its …

Eosinophilic esophagitis (EoE) is an emerging chronic inflammatory disease of the
oesophagus and is clinically characterized by upper gastrointestinal (GI) symptoms …