Molecular mechanisms of cisplatin resistance
Platinum-based drugs, and in particular cis-diamminedichloroplatinum (II)(best known as
cisplatin), are employed for the treatment of a wide array of solid malignancies, including …
cisplatin), are employed for the treatment of a wide array of solid malignancies, including …
Inhibiting bacterial drug efflux pumps via phyto-therapeutics to combat threatening antimicrobial resistance
Antibiotics, once considered the lifeline for treating bacterial infections, are under threat due
to the emergence of threatening antimicrobial resistance (AMR). These drug-resistant …
to the emergence of threatening antimicrobial resistance (AMR). These drug-resistant …
Marine cyanobacteria and microalgae metabolites—A rich source of potential anticancer drugs
Cancer is at present one of the utmost deadly diseases worldwide. Past efforts in cancer
research have focused on natural medicinal products. Over the past decades, a great deal of …
research have focused on natural medicinal products. Over the past decades, a great deal of …
The potential of microalgae for the production of bioactive molecules of pharmaceutical interest
Through the photosynthetic activity, microalgae process more than 25% of annual inorganic
carbon dissolved in oceans into carbohydrates that ultimately, serve to feed the other levels …
carbon dissolved in oceans into carbohydrates that ultimately, serve to feed the other levels …
Reversal of multidrug resistance in cancer by multi-functional flavonoids
Q Ye, K Liu, Q Shen, Q Li, J Hao, F Han… - Frontiers in …, 2019 - frontiersin.org
Multidrug resistance (MDR) resulting from different defensive mechanisms in cancer is one
of the major obstacles of clinical treatment. To circumvent MDR many reversal agents have …
of the major obstacles of clinical treatment. To circumvent MDR many reversal agents have …
Drug resistance in glioblastoma: a mini review
CP Haar, P Hebbar, GC Wallace, A Das… - Neurochemical …, 2012 - Springer
Glioblastoma multiforme (GBM) is recognized as the most common and lethal form of central
nervous system cancer. Currently used surgical techniques, chemotherapeutic agents, and …
nervous system cancer. Currently used surgical techniques, chemotherapeutic agents, and …
Exploring the anti‐cancer potential of dietary phytochemicals for the patients with breast cancer: a comprehensive review
Background The most common and deadly cancer in female is breast cancer (BC) and new
incidence and deaths related to this cancer are rising. Aims Several issues, that is, high cost …
incidence and deaths related to this cancer are rising. Aims Several issues, that is, high cost …
Efflux pump inhibitors: new updates
The discovery of antibiotics ought to have ended the issue of bacterial infections, but this
was not the case as it has led to the evolution of various mechanisms of bacterial resistance …
was not the case as it has led to the evolution of various mechanisms of bacterial resistance …
Biochemical basis of anti-cancer-effects of phloretin—A natural dihydrochalcone
BY Choi - Molecules, 2019 - mdpi.com
Apple is a rich source of bioactive phytochemicals that help improve health by preventing
and/or curing many disease processes, including cancer. One of the apple polyphenols is …
and/or curing many disease processes, including cancer. One of the apple polyphenols is …
Pluronic P105/F127 mixed micelles for the delivery of docetaxel against Taxol-resistant non-small cell lung cancer: optimization and in vitro, in vivo evaluation
L Chen, X Sha, X Jiang, Y Chen, Q Ren… - International journal of …, 2013 - Taylor & Francis
The aim of this work was to establish a novel polymeric mixed micelle composed of Pluronic
P105 and F127 copolymers loaded with the poorly soluble antitumor drug docetaxel (DTX) …
P105 and F127 copolymers loaded with the poorly soluble antitumor drug docetaxel (DTX) …