Deuterium metabolic imaging (DMI) is an emerging clinically-applicable technique for the
non-invasive investigation of tissue metabolism. The generally short T 1 values of 2 H …

The growing demand for metabolism-specific imaging techniques has rekindled interest in
Deuterium (2H) Metabolic Imaging (DMI), a robust method based on administration of a …

Background Major depressive disorder is a leading cause of disability worldwide, affecting
up to 17% of the general population. The neural mechanisms of depression, however, are …

Purpose To demonstrate the feasibility of deuterium echo‐planar spectroscopic imaging
(EPSI) to accelerate 3D deuterium metabolic imaging in the human liver at 7 T. Methods A …

The compound β-lapachone, a naturally derived naphthoquinone, has been utilized as a
potent medicinal nutrient to improve health. Over the last twelve years, numerous reports …

Oncolytic viral therapy is a recent advance in cancer treatment, demonstrating promise as a
primary treatment option. To date, the secondary metabolic effects of viral infection in cancer …

Glucose is the primary fuel for the brain; its metabolism is linked with cerebral function.
Different magnetic resonance spectroscopy (MRS) techniques are available to assess …

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer‐related deaths.
Imaging plays a crucial role in the early detection of HCC, although current methods are …

The natural amino acid asparagine (Asn) is required by cells to sustain function and
proliferation. Healthy cells can synthesize Asn through asparagine synthetase (ASNS) …

Simple Summary Cancer is often characterized by profound changes in metabolism, some
of which are appropriate targets for therapeutic intervention. Many cancers overexpress the …