Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only
limited therapeutic options. CRC is not only a genetic disease with several mutations in …

Interleukins (ILs) are a major subclass of cytokines acting as molecular messengers playing
role in immune system responses via a cascade of signaling pathways. Belonging to the …

Colorectal cancer (CRC) is considered the second cause of cancer death worldwide. The
early diagnosis plays a key role in patient prognosis and subsequently overall survival …

Recently, many discoveries have elucidated the cellular and molecular diversity in the
leukemic microenvironment and improved our knowledge regarding their complex nature …

In recent years, chimeric antigen receptor T cells (CAR-T cells) have been faced with the
problems of weak proliferation and poor persistence in the treatment of some malignancies …

Abstract Interleukin-9 (IL-9)-producing CD4+ T helper cells (Th9) have been implicated in
allergy/asthma and anti-tumor immunity, yet molecular insights on their differentiation from …

Among the cytokines regulating immune cells, IL-9 has gained considerable attention for its
ability to act on multiple cell types as a regulator of beneficial and pathologic immune …

Simple Summary Interleukin-33 (IL-33) is often released from damaged cells, acting as a
danger signal. IL-33 exerts its function by interacting with its receptor suppression of …

Interleukin-33 (IL-33) is an epithelial-derived cytokine that can be released upon tissue
damage, stress, or infection, acting as an alarmin for the immune system. IL-33 has long …

Cellular metabolism is a crucial determinant of immune cell fate and function. Extensive
studies have demonstrated that metabolic decisions influence immune cell activation …