Context Invited update on the management of systemic autoimmune Graves disease (GD)
and associated Graves orbitopathy (GO). Evidence acquisition Guidelines, pertinent original …

Graves orbitopathy, also known as thyroid eye disease or thyroid-associated orbitopathy, is
visually disabling, cosmetically disfiguring and has a substantial negative impact on a …

Graves' orbitopathy (GO) is the main extrathyroidal manifestation of Graves' disease (GD).
Choice of treatment should be based on the assessment of clinical activity and severity of …

Graves' orbitopathy (GO) is the main extrathyroidal manifestation of Graves' disease, though
severe forms are rare. Management of GO is often suboptimal, largely because available …

Background Oxygen free radicals and cytokines play a pathogenic role in Graves'
orbitopathy. Methods We carried out a randomized, double-blind, placebo-controlled trial to …

Graves' ophthalmopathy (GO) is an autoimmune inflammatory disorder associated with
thyroid disease which affects ocular and orbital tissues. GO follows a biphasic course in …

Background Teprotumumab, a novel IGF-1R antibody was recently shown to significantly
reduce the signs of active Thyroid eye disease (TED). The current study reviews its efficacy …

Graves disease is an autoimmune disorder characterized by goitre, hyperthyroidism and, in
25% of patients, Graves ophthalmopathy. The hyperthyroidism is caused by thyroid …

Background: The prevalence and natural history of Graves' orbitopathy (GO) are poorly
documented. Methods: A large series of 346 patients with newly diagnosed and recent onset …

abstract Context: The administration of iv glucocorticoid pulses has been advocated as a
treatment approach for patients with inflammatory and moderate to severe Graves' …